AC T01319
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ID T01319
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DT 23.10.1994 (created); ewi.
DT 05.04.2010 (updated); pro.
CO Copyright (C), QIAGEN.
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FA ICER
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SY ICER; inducible cAMP early repressor.
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OS rat, Rattus norvegicus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G009771 Crem.
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CL C0008; bZIP; 1.1.7.1.3.8.
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SZ 120 AA; 13.4 kDa (cDNA) (calc.).
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SQ MAVTGDETDEETDLAPSHMAAATGDMPTYQIRAPTTALPQGVVMAASPGSLHSPQQLAEE
SQ ATRKRELRLMKNREAAKECRRRKKEYVKCLESRVAVLEVQNKKLIEELETLKDICSPKTD
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SC SPTREMBL #Q63897
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FT 60 117 SM00338; brlzneu.
FT 60 120 PF00170; bZIP transcription factor.
FT 62 113 PS50217; BZIP.
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SF transcript originates from P2 promoter in front of the gamma-domain of other CREM species;
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CP pineal, adrenal, pituitary gland.
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FF cAMP-inducible in R2C cells [2];
FF highly potent repressor of CREB activity;
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IN T00163 CREB-A; human, Homo sapiens.
IN T00164 CREB1; rat, Rattus norvegicus.
IN T01385 CREB1; cattle, Bos taurus.
IN T00989 CREB; mouse, Mus musculus.
IN T01127 CREB; pig, Sus scrofa.
IN T01307 CREB; hamster, Cricetulus sp.
IN T01380 CREB; mink, Mustela vison.
IN T01314 CREMalpha; mouse, Mus musculus.
IN T01315 CREMbeta; mouse, Mus musculus.
IN T01316 CREMgamma; mouse, Mus musculus.
IN T01309 CREMtau; mouse, Mus musculus.
IN T01602 CREMtaualpha; mouse, Mus musculus.
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MX M00981 V$CREBATF_Q6.
MX M00916 V$CREB_Q2_01.
MX M00801 V$CREB_Q3.
MX M00917 V$CREB_Q4_01.
MX M01820 V$CREM_Q6.
MX M08803 V$CREM_Q6_01.
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BS R30961.
BS R20172.
BS R30963.
BS R30962.
BS R01358.
BS R30960.
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DR TRANSPATH: MO000025578.
DR EMBL: S66024;
DR UniProtKB: Q63897;
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RN [1]; RE0001915.
RX PUBMED: 8397338.
RA Stehle J. H., Foulkes N. S., Molina C. A., Simonneaux V., Pevet P., Sassone-Corsi P.
RT Adrenergic signals direct rhythmic expression of transcriptional repressor CREM in the pineal gland
RL Nature 365:314-320 (1993).
RN [2]; RE0048825.
RX PUBMED: 14656211.
RA Morales V., Gonzalez-Robayna I., Hernandez I., Quintana J., Santana P., Ruiz de Galarreta C. M., Fanjul L. F.
RT The inducible isoform of CREM (inducible cAMP early repressor, ICER) is a repressor of CYP19 rat ovarian promoter.
RL J. Endocrinol. 179:417-425 (2003).
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