AC T01307
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ID T01307
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DT 22.10.1994 (created); ewi.
DT 06.05.2014 (updated); vad.
CO Copyright (C), QIAGEN.
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FA CREB
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SY CREB; Cyclic AMP Responsive Element Binging factor.
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OS hamster, Cricetulus sp.
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; cricetidae; cricetinae; cricetini
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CL C0008; bZIP; 1.1.7.1.1.
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SF several splice variants are known (by similarity with human, mouse, rat);
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FF becomes phosphorylated in hippocampal neurons upon light exposure of the animals [1];
FF in addition to enhanced activity by PKA-dependent phosphorylation, a calcium-dependent activation of calcineurin phosphatase is also necessary for full trans-activation by CREB [2];
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IN T00968 ATF-1; human, Homo sapiens.
IN T01304 ATF-1; mouse, Mus musculus.
IN T01305 CBP100; mouse, Mus musculus.
IN T00166 CREB-B; human, Homo sapiens.
IN T01314 CREMalpha; mouse, Mus musculus.
IN T00165 deltaCREB; rat, Rattus norvegicus.
IN T01319 ICER; rat, Rattus norvegicus.
IN T01384 pX; HBV, human hepatitis B virus.
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MX M07248 V$CREB1_Q3.
MX M03544 V$CREB1_Q6.
MX M00981 V$CREBATF_Q6.
MX M00039 V$CREB_01.
MX M00113 V$CREB_02.
MX M00177 V$CREB_Q2.
MX M00916 V$CREB_Q2_01.
MX M00801 V$CREB_Q3.
MX M00178 V$CREB_Q4.
MX M00917 V$CREB_Q4_01.
MX M00114 V$TAXCREB_01.
MX M00115 V$TAXCREB_02.
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BS R00471.
BS R31325.
BS R31321.
BS R21482.
BS R02456.
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DR TRANSPATH: MO000025569.
DR TRANSCOMPEL: C00107.
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RN [1]; RE0002709.
RX PUBMED: 8097062.
RA Ginty D. D., Kornhauser J. M., Thompson M. A., Bading H., Mayo K. E., Takahashi J. S., Greenberg M. E.
RT Regulation of CREB phosphorylation in the suprachiasmatic nucleus by light and a circadian clock
RL Science 260:238-241 (1993).
RN [2]; RE0006690.
RX PUBMED: 7536740.
RA Schwaninger M., Blume R., Kruger M., Lux G., Oetjen E.
RT Involvement of the Ca(2+)-dependent phosphatase calcineurin in gene transcription that is stimulated by cAMP through cAMP response elements
RL J. Biol. Chem. 270:8860-8866 (1995).
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