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AC T01350
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ID T01350
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DT 26.10.1994 (created); ewi.
DT 07.03.2012 (updated); mkl.
CO Copyright (C), QIAGEN.
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FA T3R-beta2
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SY c-ErbA-beta2; T3R-beta2; thyroid hormone receptor-beta2; TR.
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OS rat, Rattus norvegicus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G005222 Thrb.
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CL C0002; CC (rec).
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SZ 514 AA; 58.1 kDa (cDNA) (calc.).
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SQ MCMDVRCPSICTAPGSRGLASACMERVCICKAGLHLDTKMNYCVPEVHEVCPAAGSNRYM
SQ QVTDYLAYLEDSPAYSGCDVQAVPGSSIYLEQAWTLNQPYTCSYPGNLFKSKDSDLDMAL
SQ SQYSQPAHLPEEKPFPQVRSPPHSHKKGYIPSYLDKDELCVVCGDKATGYHYRCITCEGC
SQ KGFFRRTIQKSLHPSYSCKYEGKCIIDKVTRNQCQECRFKKCIYVGMATDLVLDDSKRLA
SQ KRKLIEENREKRRREELQKSIGHKPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRKFLP
SQ EDIGQAPIVNAPEGGQVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKG
SQ CCMEIMSLRAAVRYDPDSETLTLNGEMAVTRGQLKNGGLGVVSDAIFDLGMSLSSFNLDD
SQ TEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYINYRKHHVTHFWPKLLMKVTD
SQ LRMIGACHASRFLHMKVECPTELFPPLFLEVFED
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SC Swiss-Prot#P18113
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FT 73 436
PF00478; IMP dehydrogenase / GMP reductase domai.
FT 157 230
SM00399; c4gold.
FT 157 234
PS51030; NUCLEAR_REC_DBD_2.
FT 158 235
PF00105; Zinc finger, C4 type (two domains).
FT 327 485
SM00430; holi.
FT 330 511
PF00104; Ligand-binding domain of nuclear hormon.
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SF another splice variant produced by the same gene, T3R-beta1 T00853;
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CP hypothalamus; arcuate, ventromedial, paraventricular cells.
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IN T08796 ASC-2; human, Homo sapiens.
IN T08499 CBP; mouse, Mus musculus.
IN T08256 SRC-1A; human, Homo sapiens.
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MX M02119 V$T3RBETA_Q6_01.
MX M00963 V$T3R_Q6.
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BS R03952.
BS R03953.
BS R04508.
BS R03942.
BS R03102.
BS R02595.
BS R03886.
BS R00619.
BS R01617.
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DR TRANSPATH: MO000025606.
DR EMBL: M25071;
DR UniProtKB: P18113;
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RN [1]; RE0000566.
RX PUBMED: 1733708.
RA Cook C. B., Kakucska I., Lechan R. M., Koenig R. J.
RT Expression of thyroid hormone receptor beta2 in rat hypothalamus
RL Endocrinology 130:1077-1079 (1992).
RN [2]; RE0048970.
RX PUBMED: 16645037.
RA Tian H., Mahajan M. A., Wong C. T., Habeos I., Samuels H. H.
RT The N-Terminal A/B domain of the thyroid hormone receptor-beta2 isoform influences ligand-dependent recruitment of coactivators to the ligand-binding domain.
RL Mol. Endocrinol. 20:2036-2051 (2006).
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