AC T01566
XX
ID T01566
XX
DT 19.09.1995 (created); ewi.
DT 12.01.2010 (updated); jig.
CO Copyright (C), QIAGEN.
XX
FA Max-isoform3
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
XX
GE G003958 MAX; HGNC: Max.
XX
CL C0012; bHLH-ZIP.
XX
SZ 103 AA; 12.1 kDa (cDNA) (calc.), 16.5 kDa (SDS)
XX
SQ MSDNDDIEVESDEEQPRFQSAADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASR
SQ AQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQGESES
XX
SC Swiss-Prot#P61244-3
XX
FT 24 75 
PF00010; Helix-loop-helix DNA-binding domain.
FT 24 75 
PS50888; HLH.
FT 29 80 
SM00353; finulus.
XX
SF C-terminal splice variant of Max;
SF additionally both N-terminal splice variants have been found [1];
SF lacks NLS of Max and thus requires heterodimerization with c-Myc to translocate to the nucleus;
SF Max-isoform3/Max heterodimers observed only in vitro, not found in vivo [1];
XX
FF Max-isoform3 enhances the co-transforming activity of c-myc and ras [1];
XX
IN T00140 c-Myc-isoform1; human, Homo sapiens.
IN T01567 Max-isoform1; human, Homo sapiens.
IN T00489 Max-isoform2; human, Homo sapiens.
IN T01566 Max-isoform3; human, Homo sapiens.
XX
MX M01034 V$EBOX_Q6_01.
MX M00119 V$MAX_01.
MX M00118 V$MYCMAX_01.
MX M00123 V$MYCMAX_02.
MX M00615 V$MYCMAX_03.
MX M00322 V$MYCMAX_B.
MX M00799 V$MYC_Q2.
XX
DR TRANSPATH: MO000025771.
DR EMBL: X60287;
DR UniProtKB: P61244-3;
XX
RN [1]; RE0003350.
RX PUBMED: 1566084.
RA Maekelae T. P., Koskinen P. J., Vaestrik I., Alitalo K.
RT Alternative forms of Max as enhancers or suppressors of Myc-Ras cotransformation
RL Science 256:373-377 (1992).
XX
//