AC T01596
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ID T01596
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DT 28.11.1995 (created); ewi.
DT 07.06.2012 (updated); jtr.
CO Copyright (C), QIAGEN.
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FA LBP-1b
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SY LBP-1B; NF2d9; NF2d9 (mouse); UBP-1; upstream binding protein 1.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G008769 UBP1; HGNC: UBP1.
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CL C0051; Grainyhead; 6.7.2.0.3.1.
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SZ 540 AA; 60.5 kDa (cDNA) (calc.).
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SQ MAWVLKMDEVIESGLVHDFDASLSGIGQELGAGAYSMSDVLALPIFKQEDSSLPLDGETE
SQ HPPFQYVMCAATSPAVKLHDETLTYLNQGQSYEIRMLDNRKMGDMPEINGKLVKSIIRVV
SQ FHDRRLQYTEHQQLEGWKWNRPGDRLLDLDIPMSVGIIDTRTNPSQLNAVEFLWDPAKRT
SQ SAFIQVHCISTEFTPRKHGGEKGVPFRIQVDTFKQNENGEYTDHLHSASCQIKVFKPKGA
SQ DRKQKTDREKMEKRTAHEKEKYQPSYDTTILTEMRLEPIIEDAVEHEQKKSSKRTLPADY
SQ GDSLAKRGSCSPWPDAPTAYVNNSPSPAPTFTSPQQSTCSVPDSNSSSPNHQGDGASQTS
SQ GEQIQPSATIQETQQWLLKNRFSSYTRLFSNFSGADLLKLTKEDLVQICGAADGIRLYNS
SQ LKSRSVRPRLTIYVCREQPSSTVLQGQQQAASSASENGSGAPYVYHAIYLEEMIASEVAR
SQ KLALVFNIPLHQINQVYRQGPTGIHILVSDQMVQNFQDESCFLFSTVKAESSDGIHIILK
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SC translated from EMBL #AF198487
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FT 33 538 PF00478; IMP dehydrogenase / GMP reductase domain.
FT 34 261 PF04516; CP2 transcription factor.
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SF belongs to CP2 family together with human CP2/LBP-1c T00151, mouse CP2/LBP-1c T00152, mouse NF2d9/LBP-1b T01597 [1];
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CP widespread.
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FF activator [4];
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BS R14307.
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DR TRANSPATH: MO000025789.
DR EMBL: AF198487; AF198487.
DR UniProtKB: Q9NZI7-1; Q9NZI7.
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RN [1]; RE0003517.
RX PUBMED: 7623810.
RA Sueyoshi T., Kobayashi R., Nishio K., Aida K., Moore R., Wada T., Handa H., Negishi M.
RT A nuclear factor (NF2d9) that binds to the male-specific P450 (Cyp 2d-9) gene in mouse liver
RL Mol. Cell. Biol. 15:4158-4166 (1995).
RN [2]; RE0003518.
RX PUBMED: 8114710.
RA Yoon J. B., Li G., Roeder R. G.
RT Characterization of a family of related cellular transcription factors which can modulate human immunodeficiency virus type 1 trancription in vitro
RL Mol. Cell. Biol. 14:1776-1785 (1994).
RN [3]; RE0023445.
RX PUBMED: 12888489.
RA Venkatesan K., McManus H. R., Mello C. C., Smith T. F., Hansen U.
RT Functional conservation between members of an ancient duplicated transcription factor family, LSF/Grainyhead.
RL Nucleic Acids Res. 31:4304-4316 (2003).
RN [4]; RE0023447.
RX PUBMED: 10644752.
RA Huang N., Miller W. L.
RT Cloning of factors related to HIV-inducible LBP proteins that regulate steroidogenic factor-1-independent human placental transcription of the cholesterol side-chain cleavage enzyme, P450scc.
RL J. Biol. Chem. 275:2852-2858 (2000).
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