AC T01695
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ID T01695
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DT 05.03.1996 (created); ewi.
DT 16.09.2014 (updated); yre.
CO Copyright (C), QIAGEN.
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FA HOXA1
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SY Hox-1.6 (mouse); HOX1F; Xhox.lab2 (Xenopus).
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G004683 HOXA1; HGNC: HOXA1.
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HO Lab (Drosophila) T02064.
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CL C0006; homeo; 3.1.1.1.1.
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SF cooperative binding with Pbx-1 T01481 T02087 [3];
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FF most sensitively inducible by retinoic acid [1];
FF acts together with cofactor Pbx-1 T01481 T02087 as transcriptional activator [3];
FF may be involved in autism [4] [5];
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IN T01696 HOXA1; mouse, Mus musculus.
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MX M01487 V$HOXA1_01.
MX M04343 V$HOXA1_03.
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DR TRANSPATH: MO000025877.
DR UniProtKB: P49639;
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RN [1]; RE0003855.
RX PUBMED: 1675427.
RA Buettner R., Yim S. O., Hong Y. S., Boncinelli E., Tainsky M. A.
RT Alteration of homeobox gene expression by N-ras transformation of PA-1 human teratocarcinoma cells
RL Mol. Cell. Biol. 11:3573-3583 (1991).
RN [2]; RE0003856.
RX PUBMED: 7622051.
RA Hong Y. S., Kim S. Y., Bhattacharya A., Pratt D. R., Hong W. K., Tainsky M. A.
RT Structure and function of the HOX A1 human homeobox gene cDNA
RL Gene 159:209-214 (1995).
RN [3]; RE0005973.
RX PUBMED: 9218805.
RA Rocco di G., Mavilio F., Zappavigna V.
RT Functional dissection of a transcripitonally active, target-specific Hox-Pbx complex
RL EMBO J. 16:3644-3654 (1997).
RN [4]; RE0014585.
RX PUBMED: 10710787.
RA Rodier P. M.
RT The early origins of autism
RL Sci. Am. 282:56-63 (2000).
RN [5]; RE0015483.
RX PUBMED: 11091361.
RA Ingram J. L., Stodgell C. J., Hyman S. L., Figlewicz D. A., Weitkamp L. R., Rodier P. M.
RT Discovery of allelic variants of HOXA1 and HOXB1: Genetic susceptibility to autism spectrum disorders
RL Teratology 62:393-405 (2000).
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