AC T02665
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ID T02665
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DT 23.02.1999 (created); ewi.
DT 15.07.2005 (updated); ili.
CO Copyright (C), QIAGEN.
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FA NK-3
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SY Bagpipe; BAP; Bgp; NK-3.
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OS fruit fly, Drosophila melanogaster
OC eukaryota; animalia; metazoa; arthropoda; insecta; diptera; drosophiloidea; drosophilidae
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GE G018685 bap.
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HO Bapx1 (vertebrates) T02667, T02668.
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CL C0053; NK-2/Nkx.
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SZ 382 AA; 42.0 kDa (calc.).
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SQ MLNMESAGVSAAMAGLSKSLTTPFSINDILTRSNPETRRMSSVDSEPEPEKLKPSSDRER
SQ SISKSPPLCCRDLGLYKLTQPKEIQPSARQPSNYLQYYAAAMDNNNHHHQATGTSNSSAA
SQ DYMQRKLAYFGSTLAAPLDMRRCTSNDSDCDSPPPLSSSPSESPLSHDGSGLSRKKRSRA
SQ AFSHAQVFELERRFAQQRYLSGPERSEMAKSLRLTETQVKIWFQNRRYKTKRKQIQQHEA
SQ ALLGASKRVPIQVLVREDGSTTYAHMAAPGAGHGLDPALINIYRHQLQLAYGGLPLPQMQ
SQ MPFPYFYPQHKVPQPIPPPTQSSSFVTASSASSSPVPIPIPGAVRPQRTPCPSPNGQMMS
SQ VESGAESVHSAAEDVDENVEID
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SC translated from EMBL #L17133
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FT 173 233 
PS50071; HOMEOBOX_2.
FT 175 237 
SM00389; HOX_1.
FT 176 232 
PF00046; Homeobox domain.
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SF NK-2/vnd T04258, NK-3/Bagpipe and NK-4/Tinman T03612 comprise a cluster of homeobox genes and are more closely related to one another (59-66% homology) than to other Drosophila homeo domain factors [1];
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CP dorsal-most mesodermal cells giving rise to visceral mesoderm of midgut, mesodermal cells of proctodeum and stomodeum developing into visceral mesoderm of hindgut and foregut (stage 10) [2].
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FF required for normal midgut morphogenesis [2];
FF in the mesodermal cells giving rise to visceral mesoderm of midgut, Bap mRNA disappears during stage 11;
FF it persists until late stages of embryogenesis in later hindgut and foregut cells [2];
FF Bap expression is regulated by Tin [2];
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MX M02329 I$BAP_01.
MX M07766 I$BAP_02.
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BS R17507.
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DR TRANSPATH: MO000026641.
DR EMBL: L17133;
DR EMBL: M27291;
DR UniProtKB: P22809;
DR FLYBASE: FBgn0004862; bap.
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RN [1]; RE0013335.
RX PUBMED: 2573058.
RA Kim Y., Nirenberg M.
RT Drosophila NK-homeobox genes
RL Proc. Natl. Acad. Sci. USA 86:7716-7720 (1989).
RN [2]; RE0013336.
RX PUBMED: 8101173.
RA Azpiazu N., Frasch M.
RT tinman and bagpipe: two homeo box genes that determine cell fates in the dorsal mesoderm of Drosophila
RL Genes Dev. 7:1325-1340 (1993).
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