AC T02839
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ID T02839
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DT 08.12.1999 (created); mkl.
DT 01.12.2010 (updated); din.
CO Copyright (C), QIAGEN.
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FA UEF-3
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SY uPA enhancer factor 3; urokinase enhancer factor 3.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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HO NIP.
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SF complex of three subunits of 40, 50 and 64 kDa [4];
SF PKNOX1 T04122 codes for the 64 kDa subunit, the other parts are members of the Pbx proteins Pbx1a T01481, Pbx1b T02087 and Pbx-2 T04123 [5];
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FF has no transactivating properties, mediates synergism between factors binding to distant AP-1 sites [2];
FF can act as a NIP-binding factor [4];
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BS R08497.
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DR TRANSPATH: MO000026808.
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RN [1]; RE0009472.
RX PUBMED: 1330539.
RA Nerlov C., De Cesare D., Pergola F., Caracciolo A., Blasi F., Johnsen M., Verde P.
RT A regulatory element that mediates co-operation between a PEA3-AP-1 element and an AP-1 site is required for phorbol ester induction of urokinase enhancer activity in HepG2 hepatoma cells
RL EMBO J. 11:4573-4582 (1992).
RN [2]; RE0013912.
RX PUBMED: 9000129.
RA De Cesare D., Palazzolo M., Blasi F.
RT Functional characterization of COM, a DNA region required for cooperation between AP-1 sites in urokinase gene transcription
RL Oncogene 13:2551-2562 (1996).
RN [3]; RE0013913.
RX PUBMED: 9295342.
RA De Cesare D., Palazzolo M., Berthelsen J., Blasi F.
RT Characterization of UEF-4, a DNA-binding protein required for transcriptional synergism between two AP-1 sites in the human urokinase enhancer
RL J. Biol. Chem. 272:23921-23929 (1997).
RN [4]; RE0013914.
RX PUBMED: 8632000.
RA Berthelsen J., Vandekerkhove J., Blasi F.
RT Purification and characterization of UEF3, a novel factor involved in the regulation of the urokinase and other AP-1 controlled promoters
RL J. Biol. Chem. 271:3822-3830 (1996).
RN [5]; RE0015488.
RX PUBMED: 9482739.
RA Berthelsen J., Zappavigna V., Mavilio F., Blasi F.
RT Prep1, a novel functional partner of Pbx proteins
RL EMBO J. 17:1423-1433 (1998).
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