AC T03403
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ID T03403
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DT 30.05.2000 (created); rio.
DT 21.11.2012 (updated); yre.
CO Copyright (C), QIAGEN.
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FA foxo4
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SY AFX; AFX-1; AFX1; MLLT7.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G004745 FOXO4; HGNC: FOXO4.
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CL C0023; fork head; 3.3.1.15.3.
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SF translocation t(X;
SF 11)(q13;
SF q23) with the MLL (mixed-lineage leukemia) gene can cause acute leukemia [1];
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CP B-cells, T-cells [1].
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IN T09538 Smad3; Mammalia.
IN T04292 Smad4; human, Homo sapiens.
IN T13998 Smad4; Mammalia.
IN T00885 VDR; human, Homo sapiens.
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MX M00472 V$FOXO4_01.
MX M00476 V$FOXO4_02.
MX M04262 V$FOXO4_04.
MX M04263 V$FOXO4_05.
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DR TRANSPATH: MO000000904.
DR UniProtKB: P98177;
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RN [1]; RE0014558.
RX PUBMED: 9010221.
RA Borkhardt A., Repp R., Haas O. A., Leis T., Harbott J., Kreuder J., Hammermann J., Henn T., Lampert F.
RT Cloning and characterization of AFX, the gene that fuses to MLL in acute leukemias with a t(X;11)(q13;q23)
RL Oncogene 14:195-202 (1997).
RN [2]; RE0020397.
RX PUBMED: 7529552.
RA PARRY P., WEI Y., EVANS G.
RT Cloning and characterization of the t(X;11) breakpoint from a leukemic cell line identify a new member of the forkhead gene family.
RL Genes Chromosomes Cancer 11:79-84 (1994).
RN [3]; RE0030982.
RX PUBMED: 15084259.
RA Seoane J., Le H. V., Shen L., Anderson S. A., Massague J.
RT Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation.
RL Cell 117:211-23 (2004).
RN [4]; RE0070207.
RX PUBMED: 20733005.
RA An B. S., Tavera-Mendoza L. E., Dimitrov V., Wang X., Calderon M. R., Wang H. J., White J. H.
RT Stimulation of Sirt1-regulated FoxO protein function by the ligand-bound vitamin D receptor.
RL Mol. Cell. Biol. 30:4890-4900 (2010).
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