AC T03802
XX
ID T03802
XX
DT 08.09.2000 (created); rio.
DT 03.03.2014 (updated); jtr.
CO Copyright (C), QIAGEN.
XX
FA HOXB13
XX
SY homeo box B13; HOXB13.
XX
OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
XX
GE G006217 Hoxb13.
XX
HO Abd-B (Drosophila) T01476.
XX
CL C0006; homeo; 3.1.1.8.14.
XX
SF expression pattern is similar to other HOX-13 paralogs except the absence of expression in the limbs and genital tubercle [1];
SF despite its separation from the complex HOXB13 expression maintains spatial and temporal collinearity [1];
SF binds cooperatively with Meis-1T03388 T03389 and stabilizes the DNA interaction complex [2];
XX
CP (embryo 9.0 days:) caudal hindgut diverticulum, (embryo 12.5 days:) tailbud, caudal spinal cord (mantle layer), ventral grey horn, hindgut, urogenital sinus [1].
CN (embryo 12.5 days:) genital ridge, prevertebrae, genital tubercle, limbs [1].
XX
IN T03388 meis1-a; mouse, Mus musculus.
IN T03389 meis1-b; mouse, Mus musculus.
XX
MX M01467 V$HOXB13_01.
XX
DR TRANSPATH: MO000027730.
DR UniProtKB: P70321;
XX
RN [1]; RE0015053.
RX PUBMED: 8756292.
RA Zeltser L., Desplan C., Heintz N.
RT Hoxb-13: a new Hox gene in a distant region of the HOXB cluster maintains colinearity
RL Development 122:2475-2484 (1996).
RN [2]; RE0015480.
RX PUBMED: 9343407.
RA Shen W. F., Montgomery J. C., Rozenfeld S., Moskow J. J., Lawrence H. J., Buchberg A. M., Largman C.
RT AbdB-like Hox proteins stabilize DNA binding by the Meis1 homeodomain proteins
RL Mol. Cell. Biol. 17:6448-6458 (1997).
RN [3]; RE0064941.
RX PUBMED: 15617687.
RA Williams T. M., Williams M. E., Innis J. W.
RT Range of HOX/TALE superclass associations and protein domain requirements for HOXA13:MEIS interaction.
RL Dev. Biol. 277:457-471 (2005).
XX
//