TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T04019 XX ID T04019 XX DT 23.11.2000 (created); rio. DT 20.11.2007 (updated); sba. CO Copyright (C), QIAGEN. XX FA Gbx2 XX SY gastrulation and brain specific homeobox protein 2. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX GE G002047 GBX2; HGNC: GBX2. XX CL C0006; homeo; XX SF amino acid sequence is 100% identical to murine Gbx-2 and T04020 and 97% identical to chicken Gbx2 T04021 [1]; SF located on the same chromosome as En-1T02015 but not on the same locus like it is the case in mouse [3]; XX CP (cell lines:) hematopoietic cell lines K562 and SKW64 [2]. EX brain,,,fetal-3; high; Northern blot; mRNA (poly-A); [1]. EX somatic tissue,,,fetal-2; low; Northern blot; mRNA (poly-A); [1]. XX FF probably involved in CNS development [1]; XX MX M01382 V$GBX2_01. MX M04324 V$GBX2_04. XX DR TRANSPATH: MO000027928. DR UniProtKB: P52951; XX RN [1]; RE0015345. RX PUBMED: 8838315. RA Lin X., Swaroop A., Vaccarino F. M., Murtha M. T., Haas M., Ji X., Ruddle F. H., Leckman J. F. RT Characterization and sequence analysis of the human homeobox-containing gene GBX2 RL Genomics 31:335-342 (1996). RN [2]; RE0015348. RX PUBMED: 9346236. RA Kowenz-Leutz E., Herr P., Niss K., Leutz A. RT The homeobox gene GBX2, a target of the myb oncogene, mediates autocrine growth and monocyte differentiation RL Cell 91:185-195 (1997). RN [3]; RE0015373. RX PUBMED: 7903253. RA Matsui T., Hirai M., Hirano M., Kurosawa Y. RT The HOX complex neighbored by the EVX gene, as well as two other homeobox-containing genes, the GBX-class and the EN-class, are located on the same chromosomes 2 and 7 in humans RL FEBS Lett. 336:107-110 (1993). XX //