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TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T04077 XX ID T04077 XX DT 08.12.2000 (created); rio. DT 12.05.2014 (updated); mkl. CO Copyright (C), QIAGEN. XX FA TGIF XX SY 5'-TG-3' interacting factor; 5'TG3' interacting factor; TG-interacting factor. XX OS mouse, Mus musculus OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae XX GE G002126 Tgif1. XX CL C0006; homeo; 3.1.4.6.1. XX SF TALE (three amino acid loop extension) homeo domain superclass [1] [2]; SF 89% amino acid identity to human TGIF T04076 [2]; SF specifically expressed in the developing cerebellum and hippocampus [2]; XX CP (embryo 12 days:) 1. branchial arch, lung bud, duodenum, hindlimb buds, brain, (embryo 15 days:) hippocampal formation, mesenceph. vesicle, cerebellar plate, vertebra, kidney, intestine, thymus, upper molars, tongue, (adult:) prolif. cells [2]. CN (adult:) superficial zone of squamous cells, papillae, lamina propria [2]. XX FF probably regulates target genes involved in the proliferation, migration and/or differentiation of particular neuronal cell lineages in the developing brain [2]; XX IN T06379 PML; mouse, Mus musculus. IN T14622 sin3a; human, Homo sapiens. XX MX M00418 V$TGIF_01. MX M01346 V$TGIF_02. XX DR TRANSPATH: MO000013622. DR UniProtKB: P70284; XX RN [1]; RE0014544. RX PUBMED: 9336443. RA Burglin T. R. RT Analysis of TALE superclass homeobox genes (MEIS, PBC, KNOX, Iroquois, TGIF) reveals a novel domain conserved between plants and animals RL Nucleic Acids Res. 25:4173-4180 (1997). RN [2]; RE0015475. RX PUBMED: 8901052. RA Bertolino E., Wildt S., Richards G., Clerc R. G. RT Expression of a novel murine homeobox gene in the developing cerebellar external granular layer during its proliferation RL Dev. Dyn. 205:410-420 (1996). RN [3]; RE0029026. RX PUBMED: 11682623. RA Sharma M., Sun Z. RT 5'TG3' interacting factor interacts with Sin3A and represses AR-mediated transcription. RL Mol. Endocrinol. 15:1918-28 (2001). RN [4]; RE0041634. RX PUBMED: 11571228. RA Wotton D., Knoepfler P. S., Laherty C. D., Eisenman R. N., Massague J. RT The Smad transcriptional corepressor TGIF recruits mSin3 RL Cell Growth Differ. 12:457-63 (2001). RN [5]; RE0049512. RX PUBMED: 16428452. RA Bartholin L., Powers S. E., Melhuish T. A., Lasse S., Weinstein M., Wotton D. RT TGIF inhibits retinoid signaling. RL Mol. Cell. Biol. 26:990-1001 (2006). XX //