AC T06379
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ID T06379
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DT 16.12.2004 (created); cch.
DT 09.01.2014 (updated); spk.
CO Copyright (C), QIAGEN.
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FA PML
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SY 1200009E24Rik; MYL; PML; promyelocytic leukemia; RNF71; TRIM19.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G013661 Pml.
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SF splicing variants are known, e.g. PML-4 T06379 [1];
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IN T06598 AML-1; mouse, Mus musculus.
IN T00308 GATA-2; human, Homo sapiens.
IN T23090 Hex; Mammalia.
IN T02235 PEBP2alphaB1; mouse, Mus musculus.
IN T04273 Smad2; mouse, Mus musculus.
IN T04210 Smad3; mouse, Mus musculus.
IN T04077 TGIF; mouse, Mus musculus.
IN T19336 TIF1; mouse, Mus musculus.
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DR TRANSPATH: MO000045024.
DR UniProtKB: Q60953;
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RN [1]; RE0025265.
RX PUBMED: 15195100.
RA Bernardi R., Scaglioni P. P., Bergmann S., Horn H. F., Vousden K. H., Pandolfi P. P.
RT PML regulates p53 stability by sequestering Mdm2 to the nucleolus.
RL Nat. Cell Biol. 6:665-672 (2004).
RN [2]; RE0028247.
RX PUBMED: 11430826.
RA Khan M. M., Nomura T., Kim H., Kaul S. C., Wadhwa R., Shinagawa T., Ichikawa-Iwata E., Zhong S., Pandolfi P. P., Ishii S.
RT Role of PML and PML-RARalpha in Mad-mediated transcriptional repression.
RL Mol. Cell 7:1233-43 (2001).
RN [3]; RE0047360.
RX PUBMED: 10938104.
RA Tsuzuki S., Towatari M., Saito H., Enver T.
RT Potentiation of GATA-2 activity through interactions with the promyelocytic leukemia protein (PML) and the t(15;17)-generated PML-retinoic acid receptor alpha oncoprotein.
RL Mol. Cell. Biol. 20:6276-6286 (2000).
RN [4]; RE0047365.
RX PUBMED: 9794812.
RA Carlile G. W., Tatton W. G., Borden K. L.
RT Demonstration of a RNA-dependent nuclear interaction between the promyelocytic leukaemia protein and glyceraldehyde-3-phosphate dehydrogenase.
RL Biochem. J. 335:691-696 (1998).
RN [5]; RE0047752.
RX PUBMED: 10610177.
RA Zhong S., Delva L., Rachez C., Cenciarelli C., Gandini D., Zhang H., Kalantry S., Freedman L. P., Pandolfi P. P.
RT A RA-dependent, tumour-growth suppressive transcription complex is the target of the PML-RARalpha and T18 oncoproteins.
RL Nat. Genet. 23:287-295 (1999).
RN [6]; RE0047880.
RX PUBMED: 15356634.
RA Lin H. K., Bergmann S., Pandolfi P. P.
RT Cytoplasmic PML function in TGF-beta signalling.
RL Nature 431:205-211 (2004).
RN [7]; RE0048859.
RX PUBMED: 10684855.
RA Zhong S., Salomoni P., Ronchetti S., Guo A., Ruggero D., Pandolfi P. P.
RT Promyelocytic leukemia protein (PML) and Daxx participate in a novel nuclear pathway for apoptosis.
RL J. Exp. Med. 191:631-640 (2000).
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