AC T04143
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ID T04143
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DT 29.12.2000 (created); rio.
CO Copyright (C), QIAGEN.
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FA Vsx-1
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SY Chx10; G10.
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OS goldfish, Carassius auratus
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Teleostomi; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Euteleostei; Ostariophysi; Cypriniformes; Cyprinoidea; Cyprinidae; Cyprininae; Carassius
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HO ceh-10 T02980 (C. elegans).
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CL C0006; homeo.
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SZ 341 AA; 37.5 kDa (cDNA) (calc.).
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SQ MTGREEAIDEKPKVKLYPSFGIDKARLNGSGFRSKGFAITDLLGLESDLQPHQSGSGAGA
SQ NGEGQSAALGGFAFPGGSLPIGLGFLCSLAAQQPPGAPCFLPSHIPLLQPRTESHFMQNL
SQ EQQRDAYSDDDCLSGDRNDGKNSQKRKKRRHRTVFTSHQLEELEKAFHEAHYPDVYAREM
SQ LAMKTELPEDRIQVWFQNRRAKWRKREKCWGRSSVMAEYGLYGAMVRHSIPLPESIINSA
SQ KNGMMGSCAPWLLGEPAGMHKKSLEIGKNPPGTPESTHSDSYSEEHKVKDSDTTWSSGAN
SQ GADDSEDMAIDLSSTSKQESKSTLKRSPPHTEDSSDSETES
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SC translated from EMBL #U07056
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FT 146 206 
PS50071; HOMEOBOX_2.
FT 148 204 
PS50552; PAX.
FT 148 210 
SM00389; HOX_1.
FT 149 205 
PF00046; Homeobox domain.
FT 208 268 
CVC domain [2].
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SF contains CVC domain which is a conserved region in Chx10/Vsx-1 T04139 T02970 T04143 T04144 and ceh-10 T02980 [2];
SF retinal injury leads to upregulation of Vsx-1 during regeneration [3];
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CP bipolar cells of inner nuclear layer [3].
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FF may stabilize the differentiated state of a subset of cells in the inner nuclear layer [3];
FF may be involved in cellular differentiation during retinal development and regeneration [3];
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DR TRANSPATH: MO000028045.
DR EMBL: U07056;
DR UniProtKB: Q90277;
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RN [1]; RE0015361.
RX PUBMED: 8096640.
RA Levine E. M., Schechter N.
RT Homeobox genes are expressed in the retina and brain of adult goldfish
RL Proc. Natl. Acad. Sci. USA 90:2729-2733 (1993).
RN [2]; RE0015515.
RX PUBMED: 7789259.
RA Svendsen P. C., McGhee J. D.
RT The C. elegans neuronally expressed homeobox gene ceh-10 is closely related to genes expressed in the vertebrate eye
RL Development 121:1253-1262 (1995).
RN [3]; RE0015516.
RX PUBMED: 7836564.
RA Levine E. M., Hitchcock P. F., Glasgow E., Schechter N.
RT Restricted expression of a new paired-class homeobox gene in normal and regenerating adult goldfish retina
RL J. Comp. Neurol. 348:596-606 (1994).
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