AC T02980
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ID T02980
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DT 22.02.2000 (created); rio.
CO Copyright (C), QIAGEN.
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FA ceh-10
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SY C. elegans homeobox 10.
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OS Caenorhabditis elegans
OC eukaryota; animalia; metazoa; nematoda; secernentea; rhabditia; rhabditida; rhabditina; rhabditoidea; rhabditidae
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HO Chx10/Vsx-1 (vertebrates).
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CL C0006; homeo.
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SZ 344 AA; 38.3 kDa (cDNA) (calc.).
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SQ MAVDEMQLAASMQMSNQMSNSQRMSFAIHEILGIQGNAYLSHGYCPQGTFLSNQPNFMDI
SQ GSCGVSGFDRQLCGTDSIGNAPAPLMYRMPISTSEVITSEPQTHVSSSSILSSATTSNSS
SQ GGGSSGGGGKASKRKKRRHRTIFTQYQIDELEKAFQDSHYPDIYAREVLAGKTELQEDRI
SQ QVWFQNRRAKWRKTEKTWGKSTIMAEYGLYGAMVRHSLPLPETITKSAEAADPQQSAAPW
SQ LLGMHKKSMEAAAHLESVEKCDMSDSDDDDRPVTPPVQRQVKNEYKPRIIEHVQQQAPQH
SQ QSSLNFDTSLVVSSSLSQLHFQDSQMIPNNNASLKLYHDYNNPM
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SC translated from EMBL #U19995
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FT 26 33 conserved octapeptide [2].
FT 71 340 PF00478; IMP dehydrogenase / GMP reductase domain.
FT 134 194 PS50071; HOMEOBOX_2.
FT 136 192 PS50552; PAX.
FT 136 198 SM00389; HOX_1.
FT 137 193 PF00046; Homeobox domain.
FT 196 253 CVC domain [2].
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SF present in embryonic RNA [1];
SF contains CVC domain which is a conserved region in Chx10/Vsx-1 T04139 T02970 T04143 T04144 and ceh-10 [2];
SF expression in AIY(R/L) interneurons may represent homologs of bipolar cells of the vertebrate retina where the homologous factor Chx10 T02970 T04139 T04142 is expressed [2];
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CP (proliferation stage:) 1-12 nuclei at the anterior pole, (L1 larva:) AIYL, AIYR, CEPDL, CEPDR, RID, ALA, RMED, AINL, AINR, AVJL, AVJR, CAN [2].
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FF may be involved in the formation and function of a subset of neuronal cells [2];
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MX M02382 N$TTX3CEH10_01.
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DR TRANSPATH: MO000026931.
DR EMBL: U19995;
DR EMBL: U50184;
DR EMBL: X52812;
DR UniProtKB: P41935;
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RN [1]; RE0014118.
RX PUBMED: 1978282.
RA Hawkins N. C., McGhee J. D.
RT Homeobox containing genes in the nematode Caenorhabditis elegans
RL Nucleic Acids Res. 18:6101-6106 (1990).
RN [2]; RE0015515.
RX PUBMED: 7789259.
RA Svendsen P. C., McGhee J. D.
RT The C. elegans neuronally expressed homeobox gene ceh-10 is closely related to genes expressed in the vertebrate eye
RL Development 121:1253-1262 (1995).
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