AC T04303
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ID T04303
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DT 07.02.2001 (created); rio.
DT 14.04.2009 (updated); ach.
CO Copyright (C), QIAGEN.
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FA lmx1b
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SY LIM homeobox transcription factor 1 beta; Lmx1.1; LMX1.2; LMX1B.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G006365 Lmx1b.
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CL C0025; LIM-homeo; 3.1.5.6.2.
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SF expression pattern correlates well with the human nail-patella syndrome caused by LMX1B T04293 mutation [1];
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CP (embryo 12.5-16.5 days:) dorsal forelimb mesenchyme, patellar mesenchyme, AP-gradient in digits [1].
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FF specification of dorsal limb cell differentiation [1];
FF induces Ptx3 T04305 expression and forms an Nr4a2 T04312 independent pathway of dopaminergic neuron development [2];
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MX M01363 V$LMX1B_01.
MX M07386 V$LMX1_Q2.
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DR TRANSPATH: MO000028161.
DR UniProtKB: O88609;
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RN [1]; RE0015731.
RX PUBMED: 10767331.
RA Dreyer S. D., Morello R., German M. S., Zabel B., Winterpacht A., Lunstrum G. P., Horton W. A., Oberg K. C., Lee B.
RT LMX1B transactivation and expression in nail-patella syndrome
RL Hum. Mol. Genet. 9:1067-1074 (2000).
RN [2]; RE0015733.
RX PUBMED: 10725922.
RA Smidt M. P., Asbreuk C. H., Cox J. J., Chen H., Johnson R. L., Burbach J. P.
RT A second independent pathway for development of mesencephalic dopaminergic neurons requires Lmx1b
RL Nat. Neurosci. 3:337-341 (2000).
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