TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T04336 XX ID T04336 XX DT 20.02.2001 (created); rio. DT 15.04.2013 (updated); mkl. CO Copyright (C), QIAGEN. XX FA Nkx2-8 XX SY Nkx-2.8; NKX2-8; NKX2G. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX GE G004559 NKX2-8; HGNC: NKX2-8. XX HO tinman T03612 (Drosophila). XX CL C0053; NK-2/Nkx; XX SF most closely related to TTF-1 T00857 and NKX2B T04337 [2]; SF may be the alpha-fetoprotein (AFP) regulator PCF [2] [1]; XX CP (cell lines:) hepatocarcinoma cell lines HepG2, HuH7 and Clone 2 [2]. CN (cell lines:) R7451 [2]. EX blood,,,adult; very low; RT-PCR; mRNA (poly-A); [2]. EX liver,,,adult; none; RT-PCR; mRNA (poly-A); [2]. EX liver,,,adult; very low; Northern blot; mRNA (poly-A); [2]. EX liver,,,fetal; low; RT-PCR; mRNA (poly-A); [2]. EX liver,,,fetal; very low; Northern blot; mRNA (poly-A); [2]. EX lung (right and left),,,adult; none; Northern blot; mRNA (poly-A); [2]. EX lung (right and left),,,adult; very low; RT-PCR; mRNA (poly-A); [2]. EX spleen,,,adult; none; Northern blot; mRNA (poly-A); [2]. XX FF transcriptional activator [2]; FF associated with liver development and alpha-fetoprotein (AFP) expression [2]; XX MX M04412 V$NKX28_01. XX BS R14700. XX DR TRANSPATH: MO000028194. DR UniProtKB: O15522; XX RN [1]; RE0009815. RX PUBMED: 7523856. RA Wen P., Locker J. RT A novel hepatocytic transcription factor that binds the alpha-fetoprotein promoter-linked coupling element RL Mol. Cell. Biol. 14:6616-6626 (1994). RN [2]; RE0015773. RX PUBMED: 9446603. RA Apergis G. A., Crawford N., Ghosh D., Steppan C. M., Vorachek W. R., Wen P., Locker J. RT A novel nk-2-related transcription factor associated with human fetal liver and hepatocellular carcinoma RL J. Biol. Chem. 273:2917-2925 (1998). XX //