AC T04815
AS T15130.
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ID T04815
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DT 10.10.2001 (created); mas.
DT 24.06.2011 (updated); jtr.
CO Copyright (C), QIAGEN.
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FA FOXP1
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SY forkhead-related transcription factor 1; FOXP1; glutamine (Q)-rich factor 1; QRF1.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G002814 Foxp1.
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CL C0023; fork head; 3.3.1.16.1.
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SF generic entry of four different splice variants T04811, T04812, T04813, T05943 [1] [2];
SF tissue-specific alternative splicing [2];
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CP broadly expressed, with different tissue distribution of different splice variants [1] [2].
EX alveolar epithelium of left lung,,,Theiler Stage 20; high; RNA-in situ hybridization (not further specified); RNA (undefined); [1].
EX alveolar epithelium of left lung,,,Theiler Stage 22; high; RNA-in situ hybridization (not further specified); RNA (undefined); [1].
EX alveolar epithelium of left lung,,,Theiler Stage 24; high; RNA-in situ hybridization (not further specified); RNA (undefined); [1].
EX alveolar epithelium of right lung,,,Theiler Stage 20; high; RNA-in situ hybridization (not further specified); RNA (undefined); [1].
EX alveolar epithelium of right lung,,,Theiler Stage 22; high; RNA-in situ hybridization (not further specified); RNA (undefined); [1].
EX alveolar epithelium of right lung,,,Theiler Stage 24; high; RNA-in situ hybridization (not further specified); RNA (undefined); [1].
EX atrium of heart (right and left),,,Theiler Stage 22; none; RNA-in situ hybridization (not further specified); RNA (undefined); [1].
EX atrium of heart (right and left),,,Theiler Stage 24; none; RNA-in situ hybridization (not further specified); RNA (undefined); [1].
EX brain,,,adult; high; Northern blot; total RNA; [1].
EX cerebral hemisphere (right and left),,,Theiler Stage 24; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [1].
EX epithelial lamina of large intestine,,,Theiler Stage 20; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [1].
EX epithelial lamina of large intestine,,,Theiler Stage 24; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [1].
EX heart,,,adult; low; Northern blot; total RNA; [1].
EX interneurons of spinal cord,,,Theiler Stage 20; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [1].
EX kidney (right and left),,,adult; low; Northern blot; total RNA; [1].
EX liver,,,adult; low; Northern blot; total RNA; [1].
EX lung,,,adult; high; Northern blot; total RNA; [1].
EX mesenchyme of left lung,,,Theiler Stage 20; high; RNA-in situ hybridization (not further specified); RNA (undefined); [1].
EX mesenchyme of left lung,,,Theiler Stage 22; high; RNA-in situ hybridization (not further specified); RNA (undefined); [1].
EX mesenchyme of left lung,,,Theiler Stage 24; high; RNA-in situ hybridization (not further specified); RNA (undefined); [1].
EX mesenchyme of right lung,,,Theiler Stage 20; high; RNA-in situ hybridization (not further specified); RNA (undefined); [1].
EX mesenchyme of right lung,,,Theiler Stage 22; high; RNA-in situ hybridization (not further specified); RNA (undefined); [1].
EX mesenchyme of right lung,,,Theiler Stage 24; high; RNA-in situ hybridization (not further specified); RNA (undefined); [1].
EX mesodermal layer of developing large intestine,,,Theiler Stage 20; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [1].
EX mesodermal layer of developing large intestine,,,Theiler Stage 24; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [1].
EX motorneurons of spinal cord,,,Theiler Stage 20; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [1].
EX muscles,,,adult; low; Northern blot; total RNA; [1].
EX outer cortical plate of the neopallial cortex,,,Theiler Stage 24; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [1].
EX outflow tract of heart,,,Theiler Stage 22; none; RNA-in situ hybridization (not further specified); RNA (undefined); [1].
EX outflow tract of heart,,,Theiler Stage 24; none; RNA-in situ hybridization (not further specified); RNA (undefined); [1].
EX small intestine,,,adult; low; Northern blot; total RNA; [1].
EX spleen,,,adult; high; Northern blot; total RNA; [1].
EX ventricle of heart (right and left),,,Theiler Stage 22; none; RNA-in situ hybridization (not further specified); RNA (undefined); [1].
EX ventricle of heart (right and left),,,Theiler Stage 24; none; RNA-in situ hybridization (not further specified); RNA (undefined); [1].
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FF regulates cardiac outflow tract, endocardial cushion morphogenesis and myocyte proliferation and maturation [3];
FF could repress expression of epithelial genes in the lung: reduces expression from promoters of mouse CC10 gene G002818 and human SP-C gene G002817 [1];
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MX M00987 V$FOXP1_01.
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BS R31552.
BS R70308.
BS R30296.
BS R35669.
BS R35670.
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DR TRANSPATH: MO000028622.
DR UniProtKB: P58462;
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RN [1]; RE0016948.
RX PUBMED: 11358962.
RA Shu W., Yang H., Zhang L., Lu M. M., Morrisey E. E.
RT Characterization of a new subfamily of winged-helix/forkhead (Fox) genes that are expressed in the lung and act as transcriptional repressors
RL J. Biol. Chem. 276:27488-27497 (2001).
RN [2]; RE0024165.
RX PUBMED: 12692134.
RA Wang B., Lin D., Li C., Tucker P.
RT Multiple domains define the expression and regulatory properties of Foxp1 forkhead transcriptional repressors.
RL J. Biol. Chem. 278:24259-24268 (2003).
RN [3]; RE0048527.
RX PUBMED: 15342473.
RA Wang B., Weidenfeld J., Lu M. M., Maika S., Kuziel W. A., Morrisey E. E., Tucker P. W.
RT Foxp1 regulates cardiac outflow tract, endocardial cushion morphogenesis and myocyte proliferation and maturation.
RL Development 131:4477-4487 (2004).
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