TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T05017 XX ID T05017 XX DT 13.02.2002 (created); mas. DT 12.11.2014 (updated); hna. CO Copyright (C), QIAGEN. XX FA HNF-4 XX SY AF-1; HNF4. XX OS rat, Rattus norvegicus OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae XX CL C0002; CC (rec). XX SF two isoforms (at least for human and mouse) encoded by two different genes are known: HNF-4alpha and HNF-4gamma; SF for HNF-4 alpha T05288 two splice variants are known: HNF-4alpha1 T00372, HNF-4alpha2 T02422.; XX CP (rat liver nuclear extracts). XX FF activator; FF activates genes in liver, kidney, intestine; XX IN T08300 ER-alpha-L; human, Homo sapiens. XX MX M00762 V$DR1_Q3. MX M00638 V$HNF4ALPHA_Q6. MX M00764 V$HNF4DR1_Q3. MX M00967 V$HNF4_Q6. MX M01031 V$HNF4_Q6_01. MX M01032 V$HNF4_Q6_02. MX M01033 V$HNF4_Q6_03. MX M03828 V$HNF4_Q6_04. XX BS R00114. BS R15923. BS R15845. BS R22701. BS R27847. BS R16063. BS R16067. BS R01612. BS R20717. BS R02657. BS R16069. BS R15905. BS R15898. BS R15920. BS R16051. BS R04478. BS R14385. BS R15902. BS R15904. BS R15927. BS R19280. BS R15791. BS R15846. BS R13273. BS R18860. BS R22492. BS R22494. BS R22487. BS R22489. BS R28575. BS R13070. BS R13018. BS R13065. BS R01690. BS R12074. BS R13032. BS R20539. BS R39333. BS R64853. BS R04031. XX DR TRANSPATH: MO000028775. DR TRANSCOMPEL: C00582. XX RN [1]; RE0000898. RX PUBMED: 2777781. RA Leff T., Reue K., Melian A., Culver H., Breslow J. L. RT A Regulatory Element in the ApoCIII Promoter That Directs Hepatic Specific Transcription Binds to Proteins in Expressing and Nonexpressing Cell Types RL J. Biol. Chem. 264:16132-16137 (1989). RN [2]; RE0001369. RX PUBMED: 2325658. RA Trus M., Benvenisty N., Cohen H., Reshef L. RT Developmentally Regulated Interaction of Liver Nuclear Factors with the Rat Phosphoenolpyruvate Carboxykinase Promoter RL Mol. Cell. Biol. 10:2418-2422 (1990). RN [3]; RE0002747. RX PUBMED: 2161847. RA Metzger S., Leff T., Breslow J. L. RT Nuclear factors AF-1 and C/EBP bind to the human ApoB gene promoter and modulate its transcriptional activity in hepatic cells RL J. Biol. Chem. 265:9978-9983 (1990). RN [4]; RE0010737. RX PUBMED: 7831301. RA Hall R. K., Sladek F. M., Granner D. K. RT The ophan receptors COUP-TF and HNF-4 serve a accessory factors required for induction of phosphoenolpyruvate carboxykinase gene transcription by glucocorticoids RL Proc. Natl. Acad. Sci. USA 92:412-416 (1995). RN [5]; RE0047600. RX PUBMED: 9717844. RA Lee S. K., Choi H. S., Song M. R., Lee M. O., Lee J. W. RT Estrogen receptor, a common interaction partner for a subset of nuclear receptors. RL Mol. Endocrinol. 12:1184-1192 (1998). XX //