TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T05440 XX ID T05440 XX DT 21.02.2003 (created); oke. DT 06.12.2013 (updated); asv. CO Copyright (C), QIAGEN. XX FA rfx5 XX OS mouse, Mus musculus OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae XX GE G005112 Rfx5. XX CL C0023; fork head; XX SF member of winged-helix class of helix-turn-helix superclass of factors [1]; SF DNA binding subunit of the RFX complex, for human RFX complex see T05444; SF N-terminal region is required for its association with RFXAP T05443 and RFXANK T05441 and for binding of RFX complex to X-boxes [1]; SF C-terminal domain of rfx5 mediates cooperation of RFX complex with NF-Y and transcription activation [1]; SF mouse gene could fully substitute for human rfx5 to regulate MHC-II gene expression [1]; XX FF important regulator of MHC class II gene expression; XX MX M00975 V$RFX_Q6. MX M07305 V$RFX_Q6_01. XX DR TRANSPATH: MO000034949. DR UniProtKB: Q9JL61; XX RN [1]; RE0022529. RX PUBMED: 10779326. RA Villard J., Peretti M., Masternak K., Barras E., Caretti G., Mantovani R., Reith W. RT A functionally essential domain of RFX5 mediates activation of major histocompatibility complex class II promoters by promoting cooperative binding between RFX and NF-Y. RL Mol. Cell. Biol. 20:3364-3376 (2000). XX //