TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T05742 XX ID T05742 XX DT 12.11.2003 (created); ech. DT 05.01.2015 (updated); jmh. CO Copyright (C), QIAGEN. XX FA PR XX SY NR3C3; PGR; PR; progesterone receptor. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX GE G003936 PGR; HGNC: PGR. XX CL C0002; CC (rec); XX SF alternative promoter usage and, concomitantly, alternative translation initiation gives two isoforms A T01661 and B T00696 [1]; XX FF Oligoamines treatment down-regulates the protein level in MCF-7 and T47D cells [6]; FF activator or repressor in response to progesterone; FF both PR isoforms exhibit different promoter specificity [1]; XX IN T28743 Hp1-gamma; human, Homo sapiens. IN T00759 Sp1; human, Homo sapiens. XX MX M00954 V$PR_01. MX M00957 V$PR_02. MX M00960 V$PR_Q2. MX M03799 V$PR_Q6. XX BS R27629. BS R28549. BS R65187. BS R65189. BS R31965. BS R31969. BS R72071. BS R38936. BS R40827. BS R27890. BS R34873. BS R65191. BS R23811. BS R72114. BS R72115. BS R65557. BS R61394. BS R61399. BS R37863. XX DR TRANSPATH: MO000054297. DR UniProtKB: P06401; XX RN [1]; RE0000463. RX PUBMED: 2328727. RA Kastner P., Krust A., Turcotte B., Stropp U., Tora L., Gronemeyer H., Chambon P. RT Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B RL EMBO J. 9:1603-1614 (1990). RN [2]; RE0034422. RX PUBMED: 12529333. RA Chauchereau A., Amazit L., Quesne M., Guiochon-Mantel A., Milgrom E. RT Sumoylation of the progesterone receptor and of the steroid receptor coactivator SRC-1. RL J. Biol. Chem. 278:12335-43 (2003). RN [3]; RE0035340. RX PUBMED: 11818501. RA Zhou Z. X., He B., Hall S. H., Wilson E. M., French F. S. RT Domain interactions between coregulator ARA(70) and the androgen receptor (AR). RL Mol. Endocrinol. 16:287-300 (2002). RN [4]; RE0035802. RX PUBMED: 12374744. RA Wang R. A., Mazumdar A., Vadlamudi R. K., Kumar R. RT P21-activated kinase-1 phosphorylates and transactivates estrogen receptor-alpha and promotes hyperplasia in mammary epithelium. RL EMBO J. 21:5437-5447 (2002). RN [5]; RE0047167. RX PUBMED: 15137909. RA Huang S. M., Cheng Y. S. RT Analysis of two CBP (cAMP-response-element-binding protein-binding protein) interacting sites in GRIP1 (glucocorticoid-receptor-interacting protein), and their importance for the function of GRIP1 RL Biochem. J. 382:111-9 (2004). RN [6]; RE0054081. RX PUBMED: 16679312. RA Huang Y., Keen J. C., Pledgie A., Marton L. J., Zhu T., Sukumar S., Park B. H., Blair B., Brenner K., Casero RA J. r., Davidson N. E. RT Polyamine analogues down-regulate estrogen receptor alpha expression in human breast cancer cells. RL J. Biol. Chem. 281:19055-19063 (2006). RN [7]; RE0054750. RX PUBMED: 15486045. RA Skildum A., Faivre E., Lange C. A. RT Progesterone receptors induce cell cycle progression via activation of mitogen-activated protein kinases. RL Mol. Endocrinol. 19:327-339 (2005). RN [8]; RE0064860. RX PUBMED: 16854979. RA Cintron N. S., Toft D. RT Defining the requirements for Hsp40 and Hsp70 in the Hsp90 chaperone pathway. RL J. Biol. Chem. 281:26235-26244 (2006). XX //