AC T06242
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ID T06242
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DT 29.09.2004 (created); oke.
DT 06.12.2010 (updated); mkl.
CO Copyright (C), QIAGEN.
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FA c-Myc-isoform1:Max
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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CL C0012; bHLH-ZIP.
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SF heterodimer, for individual components see human c-Myc-isoform1 T00140 and human Max T05056;
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FF activator [4];
FF binds to E-box and activates YB-1 gene [4];
FF binding to DNA may be stimulated by p73alpha [4];
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IN T03414 Miz-1; human, Homo sapiens.
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BS R31050.
BS R18820.
BS R18821.
BS R15674.
BS R19591.
BS R20537.
BS R20538.
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DR TRANSPATH: MO000031924.
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RN [1]; RE0002653.
RX PUBMED: 2006410.
RA Blackwood E. M., Eisenman R. N.
RT Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc
RL Science 251:1211-1217 (1991).
RN [2]; RE0003353.
RX PUBMED: 1730411.
RA Blackwood E. M., Luescher B., Eisenman R. N.
RT Myc and Max associate in vivo
RL Genes Dev. 6:71-80 (1992).
RN [3]; RE0003401.
RX PUBMED: 8425218.
RA Ayer D. E., Kretzner L., Eisenman R. N.
RT Mad: a heterodimeric partner for Max that antagonizes Myc transcriptional activity
RL Cell 72:211-222 (1993).
RN [4]; RE0024863.
RX PUBMED: 12080043.
RA Uramoto H., Izumi H., Ise T., Tada M., Uchiumi T., Kuwano M., Yasumoto K., Funa K., Kohno K.
RT p73 Interacts with c-Myc to regulate Y-box-binding protein-1 expression.
RL J. Biol. Chem. 277:31694-31702 (2002).
RN [5]; RE0021360.
RX PUBMED: 10022833.
RA De Sepulveda P., Okkenhaug K., Rose J. L., Hawley R. G., Dubreuil P., Rottapel R.
RT Socs1 binds to multiple signalling proteins and suppresses steel factor-dependent proliferation
RL EMBO J. 18:904-915 (1999).
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