TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T06253 XX ID T06253 XX DT 05.10.2004 (created); elf. DT 15.11.2007 (updated); bch. CO Copyright (C), QIAGEN. XX FA Otx3 XX SY ATX; Cdmx; Dmbx1; MBX; orthodenticle homolog 3 (Drosophila); otx3. XX OS mouse, Mus musculus OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae XX GE G010053 Dmbx1. XX CL C0006; homeo; XX SF Otx3 lacks the 'Otx-tail', a conserved motif of about 20 amino acids that is generally believed to confer transactivation activity in the Otx family [1]; XX CP 4,3 kb transcript in MIN6 and adult cerebellum of rat, detected from 10,5 dpc to 13,5 dpc in mouse embryos; strong expression from mouse embryos 9,5 to 11,5 dpc in the mesencephalon, diencephalon, metencephalon, myelencephalon and developing eye, indicating an expression pattern largely overlapping but distinct from those of Otx1 T02080 and Otx2 T02083 and Crx T03461 [1]. CN adult pancreatic islets, tongue, kidney, skeletal muscle, heart, RINm5F, HIT-T15, lung, liver, colon, stomach. jejunum, cerebrum [1]. XX MX M01403 V$OTX3_01. XX DR TRANSPATH: MO000043954. DR UniProtKB: Q91ZK4; Q8CH43. XX RN [1]; RE0024916. RX PUBMED: 12055180. RA Zhang Y., Miki T., Iwanaga T., Koseki Y., Okuno M., Sunaga Y., Ozaki N., Yano H., Koseki H., Seino S. RT Identification, tissue expression, and functional characterization of Otx3, a novel member of the Otx family. RL J. Biol. Chem. 277:28065-28069 (2002). XX //