AC T08358
XX
ID T08358
XX
DT 16.01.2006 (created); jma.
DT 14.03.2016 (updated); smt.
CO Copyright (C), QIAGEN.
XX
FA GATA-4
XX
SY GATA-binding factor 4.
XX
OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
XX
GE G004484 Gata4.
XX
CL C0003; CC (g).
XX
SZ 440 AA; 44.5 kDa (cDNA) (calc.).
XX
SQ MYQSLAMAANHGPPPGAYEAGGPGAFMHSAGAASSPVYVPTPRVPSSVLGLSYLQGGGSA
SQ AAAGTTSGGSSGAGPSGAGPGTQQGSPGWSQAGAEGAAYTPPPVSPRFSFPGTTGSLAAA
SQ AAAAAAREAAAYGSGGGAAGAGLAGREQYGRPGFAGSYSSPYPAYMADVGASWAAAAAAS
SQ AGPFDSPVLHSLPGRANPGRHPNLDMFDDFSEGRECVNCGAMSTPLWRRDGTGHYLCNAC
SQ GLYHKMNGINRPLIKPQRRLSASRRVGLSCANCQTTTTTLWRRNAEGEPVCNACGLYMKL
SQ HGVPRPLAMRKEGIQTRKRKPKNLNKSKTPAGPAGETLPPSSGASSGNSSNATSSSSSSE
SQ EMRPIKTEPGLSSHYGHSSSMSQTSVCVRPRALHPSSAVCSKLSPQGYASPVTQTSQASS
SQ KQDSWNSLVLADSHGDIITA
XX
SC translated from EMBL:U85046
XX
FT 1 74 
transcriptional activation domain 1 [5].
FT 1 207 
PF05349; GATA-type transcription activator, N-termina.
FT 130 177 
transcriptional activation domain 2 [5].
FT 210 260 
SM00401; ZnF_GATA.
FT 210 264 
PS50114; GATA_ZN_FINGER_2.
FT 216 250 
PF00320; GATA zinc finger.
FT 264 314 
SM00401; ZnF_GATA.
FT 264 317 
PS50114; GATA_ZN_FINGER_2.
FT 270 304 
PF00320; GATA zinc finger.
XX
IN T19612 DRIP205; mouse, Mus musculus.
IN T09068 Hey2; mouse, Mus musculus.
IN T23091 p300; Mammalia.
IN T10209 TTF-1; rat, Rattus norvegicus.
IN T18923 ZFPM2-isoform1; mouse, Mus musculus.
XX
MX M00632 V$GATA4_Q3.
MX M03549 V$GATA4_Q5_01.
MX M00789 V$GATA_Q6.
XX
BS R29588.
BS R61457.
BS R61458.
BS R16353.
BS R02797.
BS R32005.
BS R37242.
BS R02969.
BS R15268.
BS R15275.
BS R22877.
BS R22886.
BS R68187.
BS R68189.
BS R68190.
BS R68192.
BS R68193.
BS R68194.
BS R68195.
BS R65610.
BS R65611.
BS R24452.
BS R41843.
BS R08292.
BS R08290.
BS R59415.
BS R31120.
BS R15857.
BS R65486.
BS R72310.
BS R72311.
BS R72312.
BS R20755.
BS R08289.
BS R32187.
BS R42521.
BS R29127.
XX
DR TRANSPATH: MO000056930.
DR TRANSCOMPEL: C00626.
DR EMBL: M98339;
DR EMBL: U85046;
DR UniProtKB: Q08369;
XX
RN [1]; RE0018174.
RX PUBMED: 11733512.
RA Liu C., Glasser S. W., Wan H., Whitsett J. A.
RT GATA-6 and thyroid transcription factor-1 directly interact and regulate surfactant protein-C gene expression.
RL J. Biol. Chem. 277:4519-4525 (2002).
RN [2]; RE0029104.
RX PUBMED: 11724781.
RA Crawford S. E., Qi C., Misra P., Stellmach V., Rao M. S., Engel J. D., Zhu Y., Reddy J. K.
RT Defects of the heart, eye, and megakaryocytes in peroxisome proliferator activator receptor-binding protein (PBP) null embryos implicate GATA family of transcription factors.
RL J. Biol. Chem. 277:3585-92 (2002).
RN [3]; RE0041697.
RX PUBMED: 11481322.
RA Dai Y. S., Markham B. E.
RT p300 Functions as a coactivator of transcription factor GATA-4
RL J. Biol. Chem. 276:37178-85 (2001).
RN [4]; RE0051652.
RX PUBMED: 11382775.
RA Huggins G. S., Bacani C. J., Boltax J., Aikawa R., Leiden J. M.
RT Friend of GATA 2 physically interacts with chicken ovalbumin upstream promoter-TF2 (COUP-TF2) and COUP-TF3 and represses COUP-TF2-dependent activation of the atrial natriuretic factor promoter.
RL J. Biol. Chem. 276:28029-28036 (2001).
RN [5]; RE0013540.
RX PUBMED: 9079680.
RA Morrisey E. E., Ip H. S., Tang Z., Parmacek M. S.
RT GATA-4 activates transcription via two novel domains that are conserved within the GATA-4/5/6 subfamily.
RL J. Biol. Chem. 272:8515-8524 (1997).
XX
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