TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T08444 XX ID T08444 XX DT 20.01.2006 (created); res. DT 04.07.2016 (updated); ros. CO Copyright (C), QIAGEN. XX FA ATF-4 XX SY activating transcription factor 4; ATF-4; ATF4; C/ATF; CREB-2; mTR67; TAXREB67 homolog; TR67; YAVREB67. XX OS mouse, Mus musculus OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae XX GE G002875 Atf4. XX CL C0008; bZIP; XX IN T08443 AML3; mouse, Mus musculus. IN T08534 c-Fos; mouse, Mus musculus. IN T08587 c-Jun; mouse, Mus musculus. IN T09409 C/EBPbeta; mouse, Mus musculus. XX MX M00514 V$ATF4_Q2. MX M07246 V$ATF4_Q5. MX M01864 V$ATF4_Q6. MX M00981 V$CREBATF_Q6. MX M00801 V$CREB_Q3. XX BS R32279. BS R65793. BS R64467. BS R73853. BS R65149. BS R63003. BS R63005. BS R61810. BS R61808. BS R61811. BS R61812. BS R26801. BS R40443. BS R63138. BS R63141. BS R61813. BS R29487. BS R41861. BS R61809. BS R69127. BS R38734. BS R65073. BS R64430. BS R66158. BS R73850. XX DR TRANSPATH: MO000057912. DR UniProtKB: Q06507; XX RN [1]; RE0005544. RX PUBMED: 1631061. RA Chevray P. M., Nathans D. RT Protein interaction cloning in yeast: identification of mammalian proteins that react with the leucine zipper of Jun RL Proc. Natl. Acad. Sci. USA 89:5789-5793 (1992). RN [2]; RE0032328. RX PUBMED: 15109498. RA Yang X., Matsuda K., Bialek P., Jacquot S., Masuoka H. C., Schinke T., Li L., Brancorsini S., Sassone-Corsi P., Townes T. M., Hanauer A., Karsenty G. RT ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry Syndrome. RL Cell 117:387-98 (2004). RN [3]; RE0035837. RX PUBMED: 16000305. RA Xiao G., Jiang D., Ge C., Zhao Z., Lai Y., Boules H., Phimphilai M., Yang X., Karsenty G., Franceschi R. T. RT Cooperative interactions between activating transcription factor 4 and Runx2/Cbfa1 stimulate osteoblast-specific osteocalcin gene expression. RL J. Biol. Chem. 280:30689-30696 (2005). RN [4]; RE0048242. RX PUBMED: 15644333. RA Bezy O., Elabd C., Cochet O., Petersen R. K., Kristiansen K., Dani C., Ailhaud G., Amri E. Z. RT Delta-interacting protein A, a new inhibitory partner of CCAAT/enhancer-binding protein beta, implicated in adipocyte differentiation. RL J. Biol. Chem. 280:11432-11438 (2005). RN [5]; RE0063034. RX PUBMED: 19114033. RA Whitney M. L., Jefferson L. S., Kimball S. R. RT ATF4 is necessary and sufficient for ER stress-induced upregulation of REDD1 expression. RL Biochem. Biophys. Res. Commun. 379:451-455 (2009). RN [6]; RE0070662. RX PUBMED: 21768648. RA Koyanagi S., Hamdan A. M., Horiguchi M., Kusunose N., Okamoto A., Matsunaga N., Ohdo S. RT cAMP response element-mediated transcription by activating transcription factor-4 (ATF4) is essential for circadian expression of the Period2 gene. RL J. Biol. Chem. 286:32416-32423 (2011). RN [7]; RE0070798. RX PUBMED: 21148039. RA Liang Q., Deng H., Sun C. W., Townes T. M., Zhu F. RT Negative regulation of IRF7 activation by activating transcription factor 4 suggests a cross-regulation between the IFN responses and the cellular integrated stress responses. RL J. Immunol. 186:1001-1010 (2011). RN [8]; RE0071034. RX PUBMED: 20660158. RA Muaddi H., Majumder M., Peidis P., Papadakis A. I., Holcik M., Scheuner D., Kaufman R. J., Hatzoglou M., Koromilas A. E. RT Phosphorylation of eIF2alpha at serine 51 is an important determinant of cell survival and adaptation to glucose deficiency. RL Mol. Biol. Cell 21:3220-3231 (2010). XX //