AC T08990
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ID T08990
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DT 05.06.2006 (created); kau.
DT 28.08.2007 (updated); tgo.
CO Copyright (C), QIAGEN.
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FA Fra-2-isoform1
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SY Fos related antigen 2; Fos-like antigen 2; FOSL2; Fra2.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G004688 FOSL2; HGNC: FOSL2.
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CL C0008; bZIP.
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SZ 326 AA; 35.2 kDa (cDNA) (calc.).
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SQ MYQDYPGNFDTSSRGSSGSPAHAESYSSGGGGQQKFRVDMPGSGSAFIPTINAITTSQDL
SQ QWMVQPTVITSMSNPYPRSHPYSPLPGLASVPGHMALPRPGVIKTIGTTVGRRRRDEQLS
SQ PEEEEKRRIRRERNKLAAAKCRNRRRELTEKLQAETEELEEEKSGLQKEIAELQKEKEKL
SQ EFMLVAHGPVCKISPEERRSPPAPGLQPMRSGGGSVGAVVVKQEPLEEDSPSSSSAGLDK
SQ AQRSVIKPISIAGGFYGEEPLHTPIVVTSTPAVTPGTSNLVFTYPSVLEQESPASPSESC
SQ SKAHRRSSSSGDQSSDSLNSPTLLAL
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SC Swiss-Prot#P15408
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FT 122 186 
PF00170; bZIP transcription factor.
FT 122 186 
SM00338; brlzneu.
FT 124 187 
PS50217; BZIP.
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IN T00167 ATF-2-isoform1; human, Homo sapiens.
IN T18798 ATFa-isoform3; human, Homo sapiens.
IN T08776 c-Fos; human, Homo sapiens.
IN T08461 c-Jun; human, Homo sapiens.
IN T09550 CREBPA-Alpha; human, Homo sapiens.
IN T08491 JunB; human, Homo sapiens.
IN T08995 JunD; human, Homo sapiens.
IN T09646 MafB; human, Homo sapiens.
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MX M00924 V$AP1_Q2_01.
MX M00926 V$AP1_Q4_01.
MX M00925 V$AP1_Q6_01.
MX M03870 V$FRA2_Q4_01.
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DR TRANSPATH: MO000082443.
DR EMBL: X16706;
DR UniProtKB: P15408;
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RN [1]; RE0004643.
RX PUBMED: 8355695.
RA Kerppola T. K., Curran T.
RT Selective DNA bending by a variety of bZIP proteins
RL Mol. Cell. Biol. 13:5479-5489 (1993).
RN [2]; RE0004788.
RX PUBMED: 8415709.
RA Kameda T., Akahori A., Sonobe M. H., Suzuki T., Endo T., Iba H.
RT JunD mutants with spontaneously acquired transforming potential have enhanced transactivating activity in combination with Fra-2
RL Proc. Natl. Acad. Sci. USA 90:9369-9373 (1993).
RN [3]; RE0004817.
RX PUBMED: 7504176.
RA Wisdom R., Verma I. M.
RT Transformation by Fos proteins requires a C-terminal transactivation domain
RL Mol. Cell. Biol. 13:7429-7438 (1993).
RN [4]; RE0004865.
RX PUBMED: 1406676.
RA Kovary K., Bravo R.
RT Existence of different Fos/Jun complexes during the G0-to-G1 transition and during exponential growth in mouse fibroblasts: differential role of Fos proteins
RL Mol. Cell. Biol. 12:5015-5023 (1992).
RN [5]; RE0004893.
RX PUBMED: 2107490.
RA Matsui M., Tokuhara M., Konuma Y., Nomura N., Ishizaki R.
RT Isolation of human fos- related genes and their expression during monocyte-macrophage differentiation
RL Oncogene 5:249-255 (1990).
RN [6]; RE0048287.
RX PUBMED: 12805554.
RA Newman J. R., Keating A. E.
RT Comprehensive identification of human bZIP interactions with coiled-coil arrays.
RL Science 300:2097-2101 (2003).
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