AC T09280
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ID T09280
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DT 30.08.2006 (created); lyn.
DT 30.11.2015 (updated); hna.
CO Copyright (C), QIAGEN.
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FA NeuroD
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SY Beta2.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G009272 Neurod1.
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CL C0010; bHLH.
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SZ 357 AA; 40.0 kDa (cDNA) (calc.).
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SQ MTKSYSESGLMGEPQPQGPPSWTDECLSSQDEEHEADKKEDELEAMNAEEDSLRNGGEEE
SQ EEDEDLEEEEEEEEEEEDQKPKRRGPKKKKMTKARLERFKLRRMKANARERNRMHGLNAA
SQ LDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRSGKSPDLVSFVQTLCKGLSQPT
SQ TNLVAGCLQLNPRTFLPEQNPDMPPHLPTASASFPVHPYSYQSPGLPSPPYGTMDSSHVF
SQ HVKPPPHAYSAALEPFFESPLTDCTSPSFDGPLSPPLSINGNFSFKHEPSAEFEKNYAFT
SQ MHYPAATLAGPQSHGSIFSSGAAAPRCEIPIDNIMSFDSHSHHERVMSAQLNAIFHD
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SC partial sequence conceptually translated from EMBL/GenBank/DDBJ #U28068 and #U28888
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FT 102 154 
PF00010; Helix-loop-helix DNA-binding domain.
FT 102 154 
PS50888; HLH.
FT 107 159 
SM00353; finulus.
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IN T00108 C/EBPalpha-isoform1; rat, Rattus norvegicus.
IN T08664 C/EBPalpha; Mammalia.
IN T05421 E47; golden (Syrian) hamster, Mesocricetus auratus.
IN T10381 ipf1; golden (Syrian) hamster, Mesocricetus auratus.
IN T09128 LAP*-NF-M; chick, Gallus gallus.
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MX M01287 V$NEUROD_01.
MX M01288 V$NEUROD_02.
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BS R70470.
BS R70471.
BS R70472.
BS R70511.
BS R70512.
BS R70473.
BS R70474.
BS R70475.
BS R70476.
BS R70477.
BS R70478.
BS R70513.
BS R70514.
BS R70515.
BS R70516.
BS R70520.
BS R70522.
BS R70523.
BS R70525.
BS R70526.
BS R36117.
BS R70503.
BS R70504.
BS R70505.
BS R70509.
BS R70510.
BS R14664.
BS R14678.
BS R30812.
BS R30813.
BS R31175.
BS R70506.
BS R70507.
BS R70508.
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DR TRANSPATH: MO000085978.
DR EMBL: U28068;
DR EMBL: U28888;
DR UniProtKB: Q60867;
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RN [1]; RE0003634.
RX PUBMED: 7754368.
RA Lee J. E., Hollenberg S. M., Snider L., Turner D. L., Lipnick N., Weintraub H.
RT Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein
RL Science 268:836-844 (1995).
RN [2]; RE0016247.
RX PUBMED: 10629047.
RA Ohneda K., Mirmira R. G., Wang J., Johnson J. D., German M. S.
RT The homeodomain of PDX-1 mediates multiple protein-protein interactions in the formation of a transcriptional activation complex on the insulin promoter.
RL Mol. Cell. Biol. 20:900-911 (2000).
RN [3]; RE0050079.
RX PUBMED: 17254333.
RA Calella A. M., Nerlov C., Lopez R. G., Sciarretta C., von Bohlen Und Halbach O., Bereshchenko O., Minichiello L.
RT Neurotrophin/Trk receptor signaling mediates C/EBPalpha, -beta and NeuroD recruitment to immediate-early gene promoters in neuronal cells and requires C/EBPs to induce immediate-early gene transcription.
RL Neural Develop. 2:4 (2007).
RN [4]; RE0055217.
RX PUBMED: 12810726.
RA Khoo S., Griffen S. C., Xia Y., Baer R. J., German M. S., Cobb M. H.
RT Regulation of insulin gene transcription by ERK1 and ERK2 in pancreatic beta cells.
RL J. Biol. Chem. 278:32969-32977 (2003).
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