AC T05421
XX
ID T05421
XX
DT 13.02.2003 (created); oke.
DT 06.06.2008 (updated); din.
CO Copyright (C), QIAGEN.
XX
FA E47
XX
SY Pan-1; TCF-3; Transcription factor E2-alpha; Transcription factor-3; Transcription regulator Pan.
XX
OS golden (Syrian) hamster, Mesocricetus auratus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; cricetidae; cricetinae; cricetini
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GE G005067 E2A.
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CL C0010; bHLH.
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SZ 649 AA; 67.4 kDa (calc.).
XX
SQ MMNQSQRMAPVGSDKELSDLLDFSMMFPLPVANGKGRPASLAGTQFAGSGLEDRPSSGSW
SQ GNSDQNSSSFDPSRTYSEGAHFSESHNSLPSSTFLGPGLGGKSSERSAYATFGRDTSVSA
SQ LTQAGFLPGELGLSSPGPLSPSGVKSGSQYYPSYPSNPRRRAADSGLDTQSKKVRKVPPG
SQ LPSSVYPSSSGDSYGRDAAAYPSAKTPGSAYPSPFYVADGSLHPSAELWSPPSQAGFGPM
SQ LGDGSSPLPLAPGSSSVGSGTFGGLQQQERMSYQLHGSEVNGTLPAVSSFSAAPGTYGGA
SQ SGHTPPVSGADSLMGTRGTTASSSGDALGKALASIYSPDHSSNNFSPSPSTPVGSPQGLP
SQ GTSQWPRAGAPSALSPTYDGGLHGLSKMEDRLDEAIHVLRSHAVGTASDLHGLLPGHGAL
SQ TTSFPGPVPLGGRHAGLVGGGHPEDGLTSGTSLLHTHASLPSQASSLPDLSQRPPDSYGG
SQ LGRAGAPAGASEIKREEKDDEESTSVADAEEDKKDLKAPRTRTSPDESTDEVLSLEEKDL
SQ RDRERRMANNARERVRVRDINEAFRELGRICQLHLKSDKAQTKLLILQQAVQVILGLEQQ
SQ VRERNLNPKAACLKRREEEKVSGVVGDPQLALSAAHPGLGEAHNPPGHL
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SC Swiss-Prot#P98180-2
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FT 542 598 
PS50888; HLH.
FT 545 598 
PF00010; Helix-loop-helix DNA-binding domain.
FT 550 603 
SM00353; finulus.
XX
FF activator [2];
FF important for B-cell-specific transcription and acts synergistically with EBF T01112 [2];
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IN T11257 Id1; rat, Rattus norvegicus.
IN T10381 ipf1; golden (Syrian) hamster, Mesocricetus auratus.
IN T09295 MASH-1; mouse, Mus musculus.
IN T09177 MyoD; mouse, Mus musculus.
IN T01634 NeuroD; hamster, Cricetulus sp.
IN T09280 NeuroD; mouse, Mus musculus.
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MX M00693 V$E12_Q6.
MX M00804 V$E2A_Q2.
MX M00973 V$E2A_Q6.
MX M07353 V$E2A_Q6_02.
MX M00002 V$E47_01.
MX M00071 V$E47_02.
MX M01034 V$EBOX_Q6_01.
MX M00222 V$HAND1E47_01.
MX M00929 V$MYOD_Q6_01.
MX M00066 V$TAL1ALPHAE47_01.
MX M00065 V$TAL1BETAE47_01.
XX
BS R13335.
BS R13336.
BS R13337.
BS R13322.
BS R13330.
BS R13342.
BS R13344.
BS R24262.
XX
DR TRANSPATH: MO000054351.
DR TRANSCOMPEL: C00036.
DR TRANSCOMPEL: C00374.
DR TRANSCOMPEL: C00377.
DR TRANSCOMPEL: C00474.
DR UniProtKB: P98180-2;
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RN [1]; RE0016247.
RX PUBMED: 10629047.
RA Ohneda K., Mirmira R. G., Wang J., Johnson J. D., German M. S.
RT The homeodomain of PDX-1 mediates multiple protein-protein interactions in the formation of a transcriptional activation complex on the insulin promoter.
RL Mol. Cell. Biol. 20:900-911 (2000).
RN [2]; RE0022480.
RX PUBMED: 12446773.
RA Sigvardsson M., Clark D. R., Fitzsimmons D., Doyle M., Akerblad P., Breslin T., Bilke S., Li R., Yeamans C., Zhang G., Hagman J.
RT Early B-cell factor, E2A, and Pax-5 cooperate to activate the early B cell-specific mb-1 promoter.
RL J. Biol. Chem. 22:8539-8551 (2002).
XX
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