AC T09289
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ID T09289
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DT 04.09.2006 (created); lyn.
DT 16.11.2006 (updated); mkl.
CO Copyright (C), QIAGEN.
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FA HOXA13
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SY Hox-1.10.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G006212 Hoxa13.
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CL C0006; homeo.
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SZ 386 AA; 39.6 kDa (cDNA) (calc.).
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SQ MTASVLLHPRWIEPTVMFLYDNGGGLVADELNKNMEGAAAAAAAAAAAAAAGAGGGGFPH
SQ PAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPLAPGAAAAYSSAPGEAPPSAAAAA
SQ AAAAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSPCSAAAQSSSGPAALPYGYFGSGYYP
SQ CARMGPHPNAIKSCAQPASAAAAFADKYMDTAGPAAEEFSSRAKEFAFYHQGYAAGPYHH
SQ HQPVPGYLDMPVVPGLGGPGESRHEPLGLPMESYQPWALPNGWNGQMYCPKEQTQPPHLW
SQ KSTLPDVVSHPSDASSYRRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTNLS
SQ ERQVTIWFQNRRVKEKKVINKLKTTS
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SC translated from EMBL #U59322
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FT 318 378 PS50071; HOMEOBOX_2.
FT 320 382 SM00389; HOX_1.
FT 321 377 PF00046; Homeobox domain.
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IN T08914 Smad1; mouse, Mus musculus.
IN T10783 Smad1; Mammalia.
IN T09086 Smad2; mouse, Mus musculus.
IN T08915 Smad5; mouse, Mus musculus.
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MX M01430 V$HOXA13_03.
MX M07456 V$HOXA913_Q4.
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BS R18689.
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DR TRANSPATH: MO000086204.
DR EMBL: U59322;
DR UniProtKB: Q62424;
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RN [1]; RE0014509.
RX PUBMED: 8673126.
RA Mortlock D. P., Post L. C., Innis J. W.
RT The molecular basis of hypodactyly (Hd): a deletion in Hoxa 13 leads to arrest of digital arch formation
RL Nat. Genet. 13:284-289 (1996).
RN [2]; RE0048182.
RX PUBMED: 16087734.
RA Williams T. M., Williams M. E., Heaton J. H., Gelehrter T. D., Innis J. W.
RT Group 13 HOX proteins interact with the MH2 domain of R-Smads and modulate Smad transcriptional activation functions independent of HOX DNA-binding capability.
RL Nucleic Acids Res. 33:4475-4484 (2005).
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