AC T09401
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ID T09401
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DT 07.10.2006 (created); smt.
DT 29.06.2016 (updated); hna.
CO Copyright (C), QIAGEN.
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FA VDR
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SY 1,25-dihydroxyvitamin D3 receptor; NR1I1; VDR; vitamin D receptor.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G014468 Vdr.
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CL C0002; CC (rec).
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SZ 422 AA; 47.8 kDa (cDNA) (calc.).
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SQ MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTC
SQ PFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMIMKRKEEEALKDSL
SQ RPKLSEEQQHIIAILLDAHHKTYDPTYADFRDFRPPIRADVSTGSYSPRPTLSFSGDSSS
SQ NSDLYTPSLDMMEPASFSTMDLNEEGSDDPSVTLDLSPLSMLPHLADLVSYSIQKVIGFA
SQ KMIPGFRDLTSDDQIVLLKSSAIEVIMLRSNQSFTMDDMSWDCGSQDYKYDITDVSRAGH
SQ TLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAKLVEAIQDRLSNTLQT
SQ YIRCRHPPPGSHQLYAKMIQKLADLRSLNEEHSKQYRSLSFQPENSMKLTPLVLEVFGNE
SQ IS
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SC translated from EMBL #D31969
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FT 21 92 SM00399; c4gold.
FT 21 96 PS51030; NUCLEAR_REC_DBD_2.
FT 22 97 PF00105; Zinc finger, C4 type (two domains).
FT 227 389 SM00430; holi.
FT 230 416 PF00104; Ligand-binding domain of nuclear hormon.
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IN T08433 RXR-alpha; human, Homo sapiens.
IN T01332 RXR-beta; mouse, Mus musculus.
IN T22422 SRC3-xbb2; human, Homo sapiens.
IN T08496 TFIIB; human, Homo sapiens.
IN T17428 TFIIB; Mammalia.
IN T08439 TIF2; mouse, Mus musculus.
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MX M00966 V$DR3_Q4.
MX M00444 V$VDR_Q3.
MX M00961 V$VDR_Q6.
MX M03569 V$VDR_Q6_01.
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BS R31440.
BS R31447.
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DR TRANSPATH: MO000088509.
DR EMBL: D31969; MMVDR.
DR UniProtKB: P48281;
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RN [1]; RE0000117.
RX PUBMED: 2159384.
RA Schuele R., Umesono K., Mangelsdorf D. J., Bolado J., Pike J. W., Evans R. M.
RT Jun-Fos and receptors for vitamins A and D recognize a common response element in the human osteocalcin gene
RL Cell 61:497-504 (1990).
RN [2]; RE0002373.
RX PUBMED: 2835767.
RA Baker A. R., McDonnell D. P., Hughes M., Crisp T. M., Mangelsdorf D. J., Haussler M. R., Pike J. W., Shine J., O'Malley B. W.
RT Cloning and expression of full-length cDNA encoding human vitamin D receptor
RL Proc. Natl. Acad. Sci. USA 85:3294-3298 (1988).
RN [3]; RE0051983.
RX PUBMED: 12529369.
RA Barry J. B., Leong G. M., Church W. B., Issa L. L., Eisman J. A., Gardiner E. M.
RT Interactions of SKIP/NCoA-62, TFIIB, and retinoid X receptor with vitamin D receptor helix H10 residues.
RL J. Biol. Chem. 278:8224-8228 (2003).
RN [4]; RE0053013.
RX PUBMED: 15176999.
RA Kurihara N., Reddy S. V., Araki N., Ishizuka S., Ozono K., Cornish J., Cundy T., Singer F. R., Roodman G. D.
RT Role of TAFII-17, a VDR binding protein, in the increased osteoclast formation in Paget's Disease.
RL J. Bone Miner. Res. 19:1154-1164 (2004).
RN [5]; RE0053029.
RX PUBMED: 12796488.
RA Yamamoto H., Shevde N. K., Warrier A., Plum L. A., DeLuca H. F., Pike J. W.
RT 2-Methylene-19-nor-(20S)-1,25-dihydroxyvitamin D3 potently stimulates gene-specific DNA binding of the vitamin D receptor in osteoblasts.
RL J. Biol. Chem. 278:31756-31765 (2003).
RN [6]; RE0053091.
RX PUBMED: 18287530.
RA Fujita H., Sugimoto K., Inatomi S., Maeda T., Osanai M., Uchiyama Y., Yamamoto Y., Wada T., Kojima T., Yokozaki H., Yamashita T., Kato S., Sawada N., Chiba H.
RT Tight Junction Proteins Claudin-2 and -12 Are Critical for Vitamin D-dependent Ca2+ Absorption between Enterocytes.
RL Mol. Biol. Cell 19:1912-1921 (2008).
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