AC T11119
XX
ID T11119
XX
DT 15.11.2007 (created); kma.
DT 27.03.2015 (updated); pro.
CO Copyright (C), QIAGEN.
XX
FA SIP1
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SY SMAD-interacting protein 1; SMADIP1; ZFX1B; ZFXH1B; zinc finger homeobox protein 1b.
XX
OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G006888 Zeb2.
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CL C0006; homeo.
XX
SZ 1215 AA; 136.5 kDa (calc.).
XX
SQ MKQPIMADGPRCKRRKQANPRRKNVVNYDNVVDAGSETDEEDKLHIAEDDSLANPLDQDT
SQ SPASMPNHESSPHMSQGLLPREEEEEELRESVVEHSWHSGEILQASVAGPEEMKEDYDAM
SQ GPEATIQTTINNGTVKNANCTSDFEEYFAKRKLEERDGHAVSIEEYLQRSDTAIIYPEAP
SQ EELSRLGTPEANGQEENDLPPGTPDAFAQLLTCPYCDRGYKRLTSLKEHIKYRHEKNEEN
SQ FSCPLCSYTFAYRTQLERHMVTHKPGTDQHQMLTQGAGNRKFKCTECGKAFKYKHHLKEH
SQ LRIHSGEKPYECPNCKKRFSHSGSYSSHISSKKCIGLISVNGRMRNNIKTGSSPNSVSSS
SQ PTNSAITQLRNKLENGKPLSMSEQTGLLKIKTEPLDFNDYKVLMATHGFSGSSPFMNGGL
SQ GATSPLGVHPSAQSPMQHLGVGMEAPLLGFPTMNSNLSEVQKVLQIVDNTVSRQKMDCKT
SQ EDISKLKGYHMKDPCSQPEEQGVTSPNIPPVGLPVVSHNGATKSIIDYTLEKVNEAKACL
SQ QSLTTDSRRQISNIKKEKLRTLIDLVTDDKMIENHSISTPFSCQFCKESFPGPIPLHQHE
SQ RYLCKMNEEIKAVLQPHENIVPNKAGVFVDNKALLLSSVLSEKGLTSPINPYKDHMSVLK
SQ AYYAMNMEPNSDELLKISIAVGLPQEFVKEWFEQRKVYQYSNSRSPSLERTSKPLAPNSN
SQ PTTKDSLLPRSPVKPMDSITSPSIAELHNSVTSCDPPLRLTKSSHFTNIKAVDKLDHSRS
SQ NTPSPLNLSSTSSKNSHSSSYTPNSFSSEELQAEPLDLSLPKQMREPKGIIATKNKTKAT
SQ SINLDHNSVSSSSENSDEPLNLTFIKKEFSNSNNLDNKSNNPVFGMNPFSAKPLYTPLPP
SQ QSAFPPATFMPPVQTSIPGLRPYPGLDQMSFLPHMAYTYPTGAATFADMQQRRKYQRKQG
SQ FQGDLLDGAQDYMSGLDDMTDSDSCLSRKKIKKTESGMYACDLCDKTFQKSSSLLRHKYE
SQ HTGKRPHQCQICKKAFKHKHHLIEHSRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRYSY
SQ CKREAEEREAAEREAREKGHLGPTELLMNRAYLQSITPQGYSDSEERESMPRDGESEKEH
SQ EKEGEEGYGKLRRRDGDEEEEEEEEESENKSMDTDPETIRDEEETGDHSMDDSSEDGKME
SQ TKSDHEEDNMEDGMG
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SC translated from EMBL #AF033116
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FT 211 234 
PF00096; zf-C2H2.
FT 211 234 
SM00355; c2h2final6.
FT 211 239 
PS50157; ZINC_FINGER_C2H2_2.
FT 241 263 
PF00096; zf-C2H2.
FT 241 263 
PS50157; ZINC_FINGER_C2H2_2.
FT 241 263 
SM00355; c2h2final6.
FT 282 304 
PF00096; zf-C2H2.
FT 282 304 
SM00355; c2h2final6.
FT 282 309 
PS50157; ZINC_FINGER_C2H2_2.
FT 310 330 
SM00355; c2h2final6.
FT 310 334 PF00096; zf-C2H2.
FT 393 1147 PF00478; IMP dehydrogenase / GMP reductase domain.
FT 437 487 interaction with MH2 domain of XSMAD-1 [1].
FT 581 601 SM00355; c2h2final6.
FT 644 706 SM00389; HOX_1.
FT 999 1021 PF00096; zf-C2H2.
FT 999 1021 SM00355; c2h2final6.
FT 999 1026 PS50157; ZINC_FINGER_C2H2_2.
FT 1027 1049 PF00096; zf-C2H2.
FT 1027 1049 SM00355; c2h2final6.
FT 1027 1054 PS50157; ZINC_FINGER_C2H2_2.
FT 1055 1076 SM00355; c2h2final6.
FT 1055 1081 PF00096; zf-C2H2.
FT 1055 1083 PS50157; ZINC_FINGER_C2H2_2.
XX
IN T08914 Smad1; mouse, Mus musculus.
IN T09086 Smad2; mouse, Mus musculus.
IN T08915 Smad5; mouse, Mus musculus.
XX
MX M08896 V$SIP1_Q6.
XX
BS R33300.
BS R33302.
BS R33303.
BS R33305.
BS R32447.
BS R32445.
BS R73334.
BS R73335.
BS R73330.
BS R73332.
BS R73342.
BS R73343.
BS R27989.
BS R66938.
BS R66934.
BS R33296.
BS R33310.
XX
DR TRANSPATH: MO000117553.
DR EMBL: AF033116;
DR UniProtKB: Q9R0G7;
XX
RN [1]; RE0017601.
RX PUBMED: 10400677.
RA Verschueren K., Remacle J. E., Collart C., Kraft H., Baker B. S., Tylzanowski P., Nelles L., Wuytens G., Su M. T., Bodmer R., Smith J. C., Huylebroeck D.
RT SIP1, a novel zinc finger/homeodomain repressor, interacts with Smad proteins and binds to 5'-CACCT sequences in candidate target genes.
RL J. Biol. Chem. 274:20489-20498 (1999).
XX
//