AC T14270
XX
ID T14270
XX
DT 10.03.2005 (created); nvo.
DT 17.12.2014 (updated); sup.
CO Copyright (C), QIAGEN.
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FA STAT5B
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OS Mammalia
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia
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IN T10446 GR; Mammalia.
IN T24182 PR; Mammalia.
IN T14458 STAT3; Mammalia.
IN T16819 STAT5A; Mammalia.
IN T09133 YY1; Mammalia.
XX
MX M00459 V$STAT5B_01.
MX M00223 V$STAT_01.
MX M00777 V$STAT_Q6.
XX
BS R23850.
BS R64635.
BS R65340.
BS R65341.
BS R29404.
XX
DR TRANSPATH: MO000047688.
DR TRANSCOMPEL: C00610.
XX
RN [1]; RE0023187.
RX PUBMED: 12089361.
RA Carsol J. L., Gingras S., Simard J.
RT Synergistic action of prolactin (PRL) and androgen on PRL-inducible protein gene expression in human breast cancer cells: a unique model for functional cooperation between signal transducer and activator of transcription-5 and androgen receptor.
RL Mol. Endocrinol. 16:1696-1710 (2002).
RN [2]; RE0025904.
RX PUBMED: 9989503.
RA Zhu M., John S., Berg M., Leonard W. J.
RT Functional association of Nmi with Stat5 and Stat1 in IL-2- and IFNgamma-mediated signaling.
RL Cell 96:121-30 (1999).
RN [3]; RE0028333.
RX PUBMED: 11238613.
RA Behbod F., Erwin-Cohen R. A., Wang M. E., Trawick B. W., Qu X., Verani R., Kahan B. D., Stepkowski S. M., Kirken R. A.
RT Concomitant inhibition of Janus kinase 3 and calcineurin-dependent signaling pathways synergistically prolongs the survival of rat heart allografts.
RL J. Immunol. 166:3724-32 (2001).
RN [4]; RE0032770.
RX PUBMED: 14684617.
RA Cao J., Wood M., Liu Y., Hoffman T., Hyde J., Park-Sarge O. K., Vore M.
RT Estradiol represses prolactin-induced expression of Na+/taurocholate cotransporting polypeptide in liver cells through estrogen receptor-alpha and signal transducers and activators of transcription 5a.
RL Endocrinology 145:1739-49 (2004).
RN [5]; RE0033348.
RX PUBMED: 12456798.
RA Le M. N., Kohanski R. A., Wang L. H., Sadowski H. B.
RT Dual mechanism of signal transducer and activator of transcription 5 activation by the insulin receptor.
RL Mol. Endocrinol. 16:2764-79 (2002).
RN [6]; RE0036012.
RX PUBMED: 15316008.
RA Duan C., Li M., Rui L.
RT SH2-B promotes insulin receptor substrate 1 (IRS1)- and IRS2-mediated activation of the phosphatidylinositol 3-kinase pathway in response to leptin.
RL J. Biol. Chem. 279:43684-43691 (2004).
RN [7]; RE0041350.
RX PUBMED: 12198240.
RA Peng B., Sutherland K. D., Sum E. Y., Olayioye M., Wittlin S., Tang T. K., Lindeman G. J., Visvader J. E.
RT CPAP is a novel stat5-interacting cofactor that augments stat5-mediated transcriptional activity
RL Mol. Endocrinol. 16:2019-33 (2002).
RN [8]; RE0041738.
RX PUBMED: 14583472.
RA Xi S., Zhang Q., Gooding W. E., Smithgall T. E., Grandis J. R.
RT Constitutive activation of Stat5b contributes to carcinogenesis in vivo
RL Cancer Res. 63:6763-71 (2003).
RN [9]; RE0042411.
RX PUBMED: 9380691.
RA White D. W., Wang D. W., Chua S. C. Jr, Morgenstern J. P., Leibel R. L., Baumann H., Tartaglia L. A.
RT Constitutive and impaired signaling of leptin receptors containing the Gln --> Pro extracellular domain fatty mutation
RL Proc. Natl. Acad. Sci. USA 94:10657-62 (1997).
RN [10]; RE0042412.
RX PUBMED: 9528750.
RA Cella N., Groner B., Hynes N. E.
RT Characterization of Stat5a and Stat5b homodimers and heterodimers and their association with the glucocortiocoid receptor in mammary cells
RL Mol. Cell. Biol. 18:1783-92 (1998).
RN [11]; RE0042416.
RX PUBMED: 9182578.
RA Kirken R. A., Malabarba M. G., Xu J., DaSilva L., Erwin R. A., Liu X., Hennighausen L., Rui H., Farrar W. L.
RT Two discrete regions of interleukin-2 (IL2) receptor beta independently mediate IL2 activation of a PD98059/rapamycin/wortmannin-insensitive Stat5a/b serine kinase
RL J. Biol. Chem. 272:15459-65 (1997).
RN [12]; RE0042419.
RX PUBMED: 12429742.
RA Kloth M. T., Laughlin K. K., Biscardi J. S., Boerner J. L., Parsons S. J., Silva C. M.
RT STAT5b, a Mediator of Synergism between c-Src and the Epidermal Growth Factor Receptor
RL J. Biol. Chem. 278:1671-9 (2003).
RN [13]; RE0055344.
RX PUBMED: 16849545.
RA Riggins R. B., Thomas K. S., Ta H. Q., Wen J., Davis R. J., Schuh N. R., Donelan S. S., Owen K. A., Gibson M. A., Shupnik M. A., Silva C. M., Parsons S. J., Clarke R., Bouton A. H.
RT Physical and functional interactions between Cas and c-Src induce tamoxifen resistance of breast cancer cells through pathways involving epidermal growth factor receptor and signal transducer and activator of transcription 5b.
RL Cancer Res. 66:7007-7015 (2006).
RN [14]; RE0070014.
RX PUBMED: 18347089.
RA Hennighausen L., Robinson G. W.
RT Interpretation of cytokine signaling through the transcription factors STAT5A and STAT5B.
RL Genes Dev. 22:711-721 (2008).
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