AC T22416
XX
ID T22416
XX
DT 24.01.2006 (created); rad.
DT 11.09.2006 (updated); sri.
CO Copyright (C), QIAGEN.
XX
FA SRC-1 (-Q)
XX
SY F-SRC-1; Hin-2 protein; NCOA-1; NCOA1; nuclear receptor coactivator 1; RIP160; SRC-1; SRC1; steroid receptor coactivator-1.
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
XX
GE G002755 NCOA1; HGNC: NCOA1.
XX
CL C0010; bHLH; 1.2.5.3.1.3.
XX
SZ 1440 AA; 156.6 kDa (cDNA) (calc.).
XX
SQ MSGLGDSSSDPANPDSHKRKGSPCDTLASSTEKRRREQENKYLEELAELLSANISDIDSL
SQ SVKPDKCKILKKTVDQIQLMKRMEQEKSTTDDDVQKSDISSSSQGVIEKESLGPLLLEAL
SQ DGFFFVVNCEGRIVFVSENVTSYLGYNQEELMNTSVYSILHVGDHAEFVKNLLPKSLVNG
SQ VPWPQEATRRNSHTFNCRMLIHPPDEPGTENQEACQRYEVMQCFTVSQPKSIQEDGEDFQ
SQ SCLICIARRLPRPPAITGVESFMTKQDTTGKIISIDTSSLRAAGRTGWEDLVRKCIYAFF
SQ QPQGREPSYARQLFQEVMTRGTASSPSYRFILNDGTMLSAHTKCKLCYPQSPDMQPFIMG
SQ IHIIDREHSGLSPQDDTNSGMSIPRVNPSVNPSISPAHGVARSSTLPPSNSNMVSTRINR
SQ QQSSDLHSSSHSNSSNSQGSFGCSPGSQIVANVALNQGQASSQSSNPSLNLNNSPMEGTG
SQ ISLAQFMSPRRQVTSGLATRPRMPNNSFPPNISTLSSPVGMTSSACNNNNRSYSNIPVTS
SQ LQGMNEGPNNSVGFSASSPVLRQMSSQNSPSRLNIQPAKAESKDNKEIASILNEMIQSDN
SQ SSSDGKPLDSGLLHNNDRLSDGDSKYSQTSHKLVQLLTTTAEQQLRHADIDTSCKDVLSC
SQ TGTSNSASANSSGGSCPSSHSSLTERHKILHRLLQEGSPSDITTLSVEPDKKDSASTSVS
SQ VTGQVQGNSSIKLELDASKKKESKDHQLLRYLLDKDEKDLRSTPNLSLDDVKVKVEKKEQ
SQ MDPCNTNPTPMTKPTPEEIKLEAQSQFTADLDQFDQLLPTLEKAAQLPGLCETDRMDGAV
SQ TSVTIKSEILPASLQSATARPTSRLNRLPELELEAIDNQFGQPGTGDQIPWTNNTVTAIN
SQ QSKSEDQCISSQLDELLCPPTTVEGRNDEKALLEQLVSFLSGKDETELAELDRALGIDKL
SQ VQGGGLDVLSERFPPQQATPPLIMEERPNLYSQPYSSPSPTANLPSPFQGMVRQKPSLGT
SQ MPVQVTPPRGAFSPGMGMQPRQTLNRPPAAPNQLRLQLQQRLQGQQQLIHQNRQAILNQF
SQ AATAPVGINMRSGMQQQITPQPPLNAQMLAQRQRELYSQQHRQRQLIQQQRAMLMRQQSF
SQ GNNLPPSSGLPVQMGNPRLPQGAPQQFPYPPNYGTNPGTPPASTSPFSQLAANPEASLAN
SQ RNSMVSRGMTGNIGGQFGTGINPQMQQNVFQYPGAGMVPQGEANFAPSLSPGSSMVPMPI
SQ PPPQSSLLQQTPPASGYQSPDMKAWQQGAIGNNNVFSQAVQNQPTPAQPGVYNNMSITVS
SQ MAGGNTNVQNMNPMMAQMQMSSLQMPGMNTVCPEQINDPALRHTGLYCNQLSSTDLLKTE
SQ ADGTQVQQVQVFADVQCTVNLVGGDPYLNQPGPLGTQKPTSGPQTPQAQQKSLLQQLLTE
XX
SC translated from EMBL:U59302
XX
FT 18 81 
PS50888; HLH.
FT 24 81 
PF00010; Helix-loop-helix DNA-binding domain.
FT 29 86 
SM00353; finulus.
FT 53 1390 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 109 180 
PS50112; PAS.
FT 111 178 
SM00091; pas_2.
FT 1149 1199 
PF07469; Domain of unknown function (DUF1518).
FT 1212 1268 
PF07469; Domain of unknown function (DUF1518).
XX
IN T08300 ER-alpha-L; human, Homo sapiens.
IN T01326 NR1B2-isoform2; human, Homo sapiens.
IN T01366 RXR-beta2; mouse, Mus musculus.
IN T00853 T3R-beta1; rat, Rattus norvegicus.
IN T08520 TBP-isoform1; human, Homo sapiens.
IN T08496 TFIIB; human, Homo sapiens.
XX
DR TRANSPATH: MO000058414.
DR EMBL: U59302; HSU59302.
DR UniProtKB: Q15788-3;
XX
RN [1]; RE0048228.
RX PUBMED: 8754792.
RA Takeshita A., Yen P. M., Misiti S., Cardona G. R., Liu Y., Chin W. W.
RT Molecular cloning and properties of a full-length putative thyroid hormone receptor coactivator.
RL Endocrinology 137:3594-3597 (1996).
XX
//