AC T28731
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ID T28731
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DT 05.04.2006 (created); res.
DT 17.02.2014 (updated); msr.
CO Copyright (C), QIAGEN.
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FA AUF1
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SY AU-rich element RNA-binding protein 1; AUF1; AUF1A; heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa); Heterogeneous nuclear ribonucleoprotein D0; hnRNP D0; hnRNPD0; HNRPD; p37.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G031517 HNRNPD; HGNC: HNRNPD.
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IN T00045 COUP-TF2; human, Homo sapiens.
IN T08494 Erg; human, Homo sapiens.
IN T22942 hnRNPA1; human, Homo sapiens.
IN T02853 hnRNPK; human, Homo sapiens.
IN T24825 HNRPL; human, Homo sapiens.
IN T29722 JKTBP; human, Homo sapiens.
IN T21984 p300; human, Homo sapiens.
IN T00794 TBP; human, Homo sapiens.
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BS R57431.
BS R60312.
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DR TRANSPATH: MO000079823.
DR UniProtKB: Q14103; HNRPD_HUMAN.
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RN [1]; RE0047532.
RX PUBMED: 12107167.
RA Pioli P. A., Hamilton B. J., Connolly J. E., Brewer G., Rigby W. F.
RT Lactate dehydrogenase is an AU-rich element-binding protein that directly interacts with AUF1.
RL J. Biol. Chem. 277:35738-35745 (2002).
RN [2]; RE0048103.
RX PUBMED: 11903055.
RA Tolnay M., Juang Y. T., Tsokos G. C.
RT Protein kinase A enhances, whereas glycogen synthase kinase-3 beta inhibits, the activity of the exon 2-encoded transactivator domain of heterogeneous nuclear ribonucleoprotein D in a hierarchical fashion.
RL Biochem. J. 363:127-136 (2002).
RN [3]; RE0052485.
RX PUBMED: 12674497.
RA Moraes K. C., Quaresma A. J., Maehnss K., Kobarg J.
RT Identification and characterization of proteins that selectively interact with isoforms of the mRNA binding protein AUF1 (hnRNP D).
RL Biol. Chem. 384:25-37 (2003).
RN [4]; RE0070421.
RX PUBMED: 21135123.
RA Sarkar S., Han J., Sinsimer K. S., Liao B., Foster R. L., Brewer G., Pestka S.
RT RNA-binding protein AUF1 regulates lipopolysaccharide-induced IL10 expression by activating IkappaB kinase complex in monocytes.
RL Mol. Cell. Biol. 31:602-615 (2011).
RN [5]; RE0070510.
RX PUBMED: 21245386.
RA Knapinska A. M., Gratacos F. M., Krause C. D., Hernandez K., Jensen A. G., Bradley J. J., Wu X., Pestka S., Brewer G.
RT Chaperone Hsp27 modulates AUF1 proteolysis and AU-rich element-mediated mRNA degradation.
RL Mol. Cell. Biol. 31:1419-1431 (2011).
RN [6]; RE0074469.
RX PUBMED: 22693611.
RA Litchfield L. M., Riggs K. A., Hockenberry A. M., Oliver L. D., Barnhart K. G., Cai J., Pierce WM J. r., Ivanova M. M., Bates P. J., Appana S. N., Datta S., Kulesza P., McBryan J., Young L. S., Klinge C. M.
RT Identification and characterization of nucleolin as a COUP-TFII coactivator of retinoic acid receptor beta transcription in breast cancer cells.
RL PLoS ONE 7:e38278 (2012).
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