AC T32444
XX
ID T32444
XX
DT 10.03.2005 (created); nvo.
DT 28.08.2015 (updated); jtr.
CO Copyright (C), QIAGEN.
XX
FA Ku80
XX
SY 86 kDa subunit of Ku antigen; ATP-dependent DNA helicase II, 80 kDa subunit; CTC box binding factor 85 kDa subunit; CTC85; CTCBF; DNA-repair protein XRCC5; G22P2; KU80; KU86; NF IV; nuclear factor IV; thyroid-lupus autoantigen; TLAA; XRCC5.
XX
OS Mammalia
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia
XX
IN T08487 AR-isoform1; human, Homo sapiens.
IN T15601 AR; Mammalia.
IN T17679 c-Myb; Mammalia.
IN T15118 CBP; Mammalia.
IN T32445 Ku70; Mammalia.
IN T23091 p300; Mammalia.
IN T08628 POU2F1; Mammalia.
IN T24182 PR; Mammalia.
IN T27800 securin; Mammalia.
IN T16163 YB-1; Mammalia.
XX
DR TRANSPATH: MO000047886.
XX
RN [1]; RE0027548.
RX PUBMED: 10608806.
RA Kim S. T., Lim D. S., Canman C. E., Kastan M. B.
RT Substrate specificities and identification of putative substrates of ATM kinase family members.
RL J. Biol. Chem. 274:37538-43 (1999).
RN [2]; RE0028036.
RX PUBMED: 10219089.
RA Yang C. R., Yeh S., Leskov K., Odegaard E., Hsu H. L., Chang C., Kinsella T. J., Chen D. J., Boothman D. A.
RT Isolation of Ku70-binding proteins (KUBs).
RL Nucleic Acids Res. 27:2165-74 (1999).
RN [3]; RE0032491.
RX PUBMED: 15100233.
RA O'Connor M. S., Safari A., Liu D., Qin J., Songyang Z.
RT The human Rap1 protein complex and modulation of telomere length.
RL J. Biol. Chem. 279:28585-91 (2004).
RN [4]; RE0036275.
RX PUBMED: 12145306.
RA Willis D. M., Loewy A. P., Charlton-Kachigian N., Shao J. S., Ornitz D. M., Towler D. A.
RT Regulation of osteocalcin gene expression by a novel Ku antigen transcription factor complex
RL J. Biol. Chem. 277:37280-91 (2002).
RN [5]; RE0040878.
RX PUBMED: 10757784.
RA Nick McElhinny S. A., Snowden C. M., McCarville J., Ramsden D. A.
RT Ku recruits the XRCC4-ligase IV complex to DNA ends
RL Mol. Cell. Biol. 20:2996-3003 (2000).
RN [6]; RE0040902.
RX PUBMED: 10783163.
RA Cooper M. P., Machwe A., Orren D. K., Brosh R. M., Ramsden D., Bohr V. A.
RT Ku complex interacts with and stimulates the Werner protein
RL Genes Dev. 14:907-12 (2000).
RN [7]; RE0040905.
RX PUBMED: 10823943.
RA Yang C. R., Leskov K., Hosley-Eberlein K., Criswell T., Pink J. J., Kinsella T. J., Boothman D. A.
RT Nuclear clusterin/XIP8, an x-ray-induced Ku70-binding protein that signals cell death
RL Proc. Natl. Acad. Sci. USA 97:5907-12 (2000).
RN [8]; RE0040907.
RX PUBMED: 12324457.
RA Lim J. W., Kim H., Kim K. H.
RT Expression of Ku70 and Ku80 mediated by NF-kappa B and cyclooxygenase-2 is related to proliferation of human gastric cancer cells
RL J. Biol. Chem. 277:46093-100 (2002).
RN [9]; RE0040910.
RX PUBMED: 15075319.
RA Wang H., Fang R., Cho J. Y., Libermann T. A., Oettgen P.
RT Positive and negative modulation of the transcriptional activity of the ETS factor ESE-1 through interaction with p300, CREB-binding protein, and Ku 70/86
RL J. Biol. Chem. 279:25241-50 (2004).
RN [10]; RE0040919.
RX PUBMED: 11985593.
RA Oh W. J., Kim E. K., Ko J. H., Yoo S. H., Hahn S. H., Yoo O. J.
RT Nuclear proteins that bind to metal response element a (MREa) in the Wilson disease gene promoter are Ku autoantigens and the Ku-80 subunit is necessary for basal transcription of the WD gene
RL Eur. J. Biochem. 269:2151-61 (2002).
RN [11]; RE0040927.
RX PUBMED: 10852966.
RA Sylla B. S., Murphy K., Cahir-McFarland E., Lane W. S., Mosialos G., Kieff E.
RT The X-linked lymphoproliferative syndrome gene product SH2D1A associates with p62dok (Dok1) and activates NF-kappa B
RL Proc. Natl. Acad. Sci. USA 97:7470-5 (2000).
RN [12]; RE0041834.
RX PUBMED: 9300672.
RA Zelazowski P., Max E. E., Kehry M. R., Snapper C. M.
RT Regulation of Ku expression in normal murine B cells by stimuli that promote switch recombination
RL J. Immunol. 159:2559-62 (1997).
RN [13]; RE0048561.
RX PUBMED: 15640154.
RA Mayeur G. L., Kung W. J., Martinez A., Izumiya C., Chen D. J., Kung H. J.
RT Ku is a novel transcriptional recycling coactivator of the androgen receptor in prostate cancer cells.
RL J. Biol. Chem. 280:10827-10833 (2005).
XX
//