TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T32444 XX ID T32444 XX DT 10.03.2005 (created); nvo. DT 28.08.2015 (updated); jtr. CO Copyright (C), QIAGEN. XX FA Ku80 XX SY 86 kDa subunit of Ku antigen; ATP-dependent DNA helicase II, 80 kDa subunit; CTC box binding factor 85 kDa subunit; CTC85; CTCBF; DNA-repair protein XRCC5; G22P2; KU80; KU86; NF IV; nuclear factor IV; thyroid-lupus autoantigen; TLAA; XRCC5. XX OS Mammalia OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia XX IN T08487 AR-isoform1; human, Homo sapiens. IN T15601 AR; Mammalia. IN T17679 c-Myb; Mammalia. IN T15118 CBP; Mammalia. IN T32445 Ku70; Mammalia. IN T23091 p300; Mammalia. IN T08628 POU2F1; Mammalia. IN T24182 PR; Mammalia. IN T27800 securin; Mammalia. IN T16163 YB-1; Mammalia. XX DR TRANSPATH: MO000047886. XX RN [1]; RE0027548. RX PUBMED: 10608806. RA Kim S. T., Lim D. S., Canman C. E., Kastan M. B. RT Substrate specificities and identification of putative substrates of ATM kinase family members. RL J. Biol. Chem. 274:37538-43 (1999). RN [2]; RE0028036. RX PUBMED: 10219089. RA Yang C. R., Yeh S., Leskov K., Odegaard E., Hsu H. L., Chang C., Kinsella T. J., Chen D. J., Boothman D. A. RT Isolation of Ku70-binding proteins (KUBs). RL Nucleic Acids Res. 27:2165-74 (1999). RN [3]; RE0032491. RX PUBMED: 15100233. RA O'Connor M. S., Safari A., Liu D., Qin J., Songyang Z. RT The human Rap1 protein complex and modulation of telomere length. RL J. Biol. Chem. 279:28585-91 (2004). RN [4]; RE0036275. RX PUBMED: 12145306. RA Willis D. M., Loewy A. P., Charlton-Kachigian N., Shao J. S., Ornitz D. M., Towler D. A. RT Regulation of osteocalcin gene expression by a novel Ku antigen transcription factor complex RL J. Biol. Chem. 277:37280-91 (2002). RN [5]; RE0040878. RX PUBMED: 10757784. RA Nick McElhinny S. A., Snowden C. M., McCarville J., Ramsden D. A. RT Ku recruits the XRCC4-ligase IV complex to DNA ends RL Mol. Cell. Biol. 20:2996-3003 (2000). RN [6]; RE0040902. RX PUBMED: 10783163. RA Cooper M. P., Machwe A., Orren D. K., Brosh R. M., Ramsden D., Bohr V. A. RT Ku complex interacts with and stimulates the Werner protein RL Genes Dev. 14:907-12 (2000). RN [7]; RE0040905. RX PUBMED: 10823943. RA Yang C. R., Leskov K., Hosley-Eberlein K., Criswell T., Pink J. J., Kinsella T. J., Boothman D. A. RT Nuclear clusterin/XIP8, an x-ray-induced Ku70-binding protein that signals cell death RL Proc. Natl. Acad. Sci. USA 97:5907-12 (2000). RN [8]; RE0040907. RX PUBMED: 12324457. RA Lim J. W., Kim H., Kim K. H. RT Expression of Ku70 and Ku80 mediated by NF-kappa B and cyclooxygenase-2 is related to proliferation of human gastric cancer cells RL J. Biol. Chem. 277:46093-100 (2002). RN [9]; RE0040910. RX PUBMED: 15075319. RA Wang H., Fang R., Cho J. Y., Libermann T. A., Oettgen P. RT Positive and negative modulation of the transcriptional activity of the ETS factor ESE-1 through interaction with p300, CREB-binding protein, and Ku 70/86 RL J. Biol. Chem. 279:25241-50 (2004). RN [10]; RE0040919. RX PUBMED: 11985593. RA Oh W. J., Kim E. K., Ko J. H., Yoo S. H., Hahn S. H., Yoo O. J. RT Nuclear proteins that bind to metal response element a (MREa) in the Wilson disease gene promoter are Ku autoantigens and the Ku-80 subunit is necessary for basal transcription of the WD gene RL Eur. J. Biochem. 269:2151-61 (2002). RN [11]; RE0040927. RX PUBMED: 10852966. RA Sylla B. S., Murphy K., Cahir-McFarland E., Lane W. S., Mosialos G., Kieff E. RT The X-linked lymphoproliferative syndrome gene product SH2D1A associates with p62dok (Dok1) and activates NF-kappa B RL Proc. Natl. Acad. Sci. USA 97:7470-5 (2000). RN [12]; RE0041834. RX PUBMED: 9300672. RA Zelazowski P., Max E. E., Kehry M. R., Snapper C. M. RT Regulation of Ku expression in normal murine B cells by stimuli that promote switch recombination RL J. Immunol. 159:2559-62 (1997). RN [13]; RE0048561. RX PUBMED: 15640154. RA Mayeur G. L., Kung W. J., Martinez A., Izumiya C., Chen D. J., Kung H. J. RT Ku is a novel transcriptional recycling coactivator of the androgen receptor in prostate cancer cells. RL J. Biol. Chem. 280:10827-10833 (2005). XX //