AC T00174
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ID T00174
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DT 15.10.1992 (created); ewi.
DT 06.01.2016 (updated); ros.
CO Copyright (C), QIAGEN.
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FA NF-1C
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SY CCAAT-binding factor; CCAAT-binding transcription factor; CTF; NF-1; TGGCA-binding protein (chick).
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G003997 NFIC; HGNC: NFIC.
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CL C0060; NF1; 7.1.2.0.3.
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SF 6 splice variants are known, for individual polypeptides see entries: NF-1 T00539, NF-1C-1 T00176, NF-1C-2 T00177, NF-1C-3 T00178, NF-1C-5 T02300, NF-1C-7 T02301 [8] [9];
SF glycosylation;
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CP HeLa, LNCaP, MCF-7, PC-3 [11]; U251, T98G [12]; T47D [10].
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IN T19424 ZFP; human, Homo sapiens.
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MX M01196 V$CTF1_01.
MX M00056 V$MYOGNF1_01.
MX M07300 V$NF1C_Q6.
MX M07363 V$NF1FAMILY_Q4.
MX M00193 V$NF1_Q6.
MX M00806 V$NF1_Q6_01.
MX M07364 V$NF1_Q6_02.
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BS R00340.
BS R03066.
BS R20775.
BS R26025.
BS R02009.
BS R02631.
BS R02634.
BS R01752.
BS R62493.
BS R00521.
BS R20754.
BS R21156.
BS R25947.
BS R24120.
BS R26339.
BS R25917.
BS R21666.
BS R20671.
BS R20672.
BS R21369.
BS R21374.
BS R28614.
BS R21847.
BS R21851.
BS R00506.
BS R15678.
BS R15679.
BS R00761.
BS R00766.
BS R00768.
BS R30409.
BS R00956.
BS R39385.
BS R03038.
BS R26029.
BS R26196.
BS R33437.
BS R26295.
BS R26297.
BS R60254.
BS R60255.
BS R25844.
BS R01455.
BS R01443.
BS R20674.
BS R21800.
BS R02209.
BS R21436.
BS R21445.
BS R16612.
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DR TRANSPATH: MO000024750.
DR UniProtKB: P08651;
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RN [1]; RE0000070.
RX PUBMED: 3024847.
RA Jones K. A., Kadonaga J. T., Rosenfeld P. J., Kelly T. J., Tjian R.
RT A cellular DNA-binding protein that activates eukaryotic transcription and replication
RL Cell 48:79-89 (1987).
RN [2]; RE0000101.
RX PUBMED: 3142689.
RA Angel P., Hattori K., Smeal T., Karin M.
RT The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1
RL Cell 55:875-885 (1988).
RN [3]; RE0000126.
RX PUBMED: 2992804.
RA Jones K. A., Yamamoto K. R., Tjian R.
RT Two distinct transcription factors that bind to the HSV thymidine kinase promoter in vitro
RL Cell 42:559-572 (1985).
RN [4]; RE0000868.
RX PUBMED: 2839477.
RA Brunel F., Ochoa A., Schaeffer E., Boissier F., Guillou Y., Cereghini S., Cohen G. N., Zakin M. M.
RT Interaction of DNA-binding Proteins with the 5' Region of the Human Transferrin Gene
RL J. Biol. Chem. 263:10180-10185 (1988).
RN [5]; RE0001283.
RX PUBMED: 2824993.
RA Greene J. M., Larin Z., Taylor I. C. A., Prentice H., Gwinn K. A., Kingston R. E.
RT Multiple Basal Elements of a Human hsp70 Promoter Function Differently in Human and Rodent Cell Lines
RL Mol. Cell. Biol. 7:3646-3655 (1987).
RN [6]; RE0001284.
RX PUBMED: 3561411.
RA Morgan W. D., Williams G. T., Morimoto R. I., Greene J., Kingston R. E., Tjian R.
RT Two transcriptional activators, CCAAT-box-binding transcription factor and heat shock transcription factor, interact with a human hsp70 gene promoter
RL Mol. Cell. Biol. 7:1129-1138 (1987).
RN [7]; RE0002363.
RX PUBMED: 2648381.
RA Jackson S. P., Tjian R.
RT Purification and analysis of RNA polymerase II transcription factors by using wheat germ agglutinin affinity chromatography
RL Proc. Natl. Acad. Sci. USA 86:1781-1785 (1989).
RN [8]; RE0003054.
RX PUBMED: 8171010.
RA Altmann H., Wendler W., Winnacker E. L.
RT Transcriptional activation by CTF proteins is mediated by a bipartite low-proline domain
RL Proc. Natl. Acad. Sci. USA 91:3901-3905 (1994).
RN [9]; RE0006390.
RX PUBMED: 8710515.
RA Wenzelides S., Altmann H., Wendler W., Winnacker E.-L.
RT CTF5- a new transcriptional activator of the NFI/CTF family
RL Nucleic Acids Res. 24:2416-2421 (1996).
RN [10]; RE0029152.
RX PUBMED: 11896613.
RA Singh J., Murata K., Itahana Y., Desprez P. Y.
RT Constitutive expression of the Id-1 promoter in human metastatic breast cancer cells is linked with the loss of NF-1/Rb/HDAC-1 transcription repressor complex.
RL Oncogene 21:1812-22 (2002).
RN [11]; RE0050557.
RX PUBMED: 12540291.
RA Yeung L. H., Read J. T., Sorenson P., Nelson C. C., Jia W., Rennie P. S.
RT Identification and characterization of a prostate-specific androgen-independent protein-binding site in the probasin promoter.
RL Biochem. J. 371:843-855 (2003).
RN [12]; RE0050593.
RX PUBMED: 10896661.
RA Bisgrove D. A., Monckton E. A., Packer M., Godbout R.
RT Regulation of brain fatty acid-binding protein expression by differential phosphorylation of nuclear factor I in malignant glioma cell lines.
RL J. Biol. Chem. 275:30668-30676 (2000).
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