AC T01124
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ID T01124
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DT 16.04.1994 (created); ewi.
DT 24.09.2013 (updated); yre.
CO Copyright (C), QIAGEN.
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FA TEF-1
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SY GT-IIC; Gtrgeo5; MCBF; mTEF-1; Sph factor; TCF13; TEA domain family member 1; TEAD-1; TEAD1; TEF-1; TEF1; transcriptional enhancer factor 1.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G013575 Tead1.
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CL C0024; TEA; 3.6.1.0.1.
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SF the TEA domain comprises three putative alpha-helices [1];
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CN lymphoid cells.
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FF activator;
FF required for normal heart development [2];
FF functionally cooperates and physically interacts with SRF upon induction of cardiac myoblast-specific transcription [6];
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IN T09276 PUR-beta; mouse, Mus musculus.
IN T09275 PUR1; mouse, Mus musculus.
IN T00764 SRF; human, Homo sapiens.
IN T00766 SRF; rat, Rattus norvegicus.
IN T22876 YAP; human, Homo sapiens.
IN T09277 YB-1; mouse, Mus musculus.
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MX M00704 V$TEF1_Q6.
MX M01817 V$TEF1_Q6_03.
MX M07340 V$TEF1_Q6_04.
MX M01305 V$TEF_01.
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BS R02075.
BS R31133.
BS R35630.
BS R31693.
BS R21550.
BS R31382.
BS R21296.
BS R34074.
BS R72761.
BS R72763.
BS R72764.
BS R39370.
BS R39371.
BS R39372.
BS R39373.
BS R01286.
BS R33769.
BS R31134.
BS R31407.
BS R31408.
BS R31135.
BS R39587.
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DR TRANSPATH: MO000013477.
DR TRANSCOMPEL: C00430.
DR UniProtKB: P30051;
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RN [1]; RE0000256.
RX PUBMED: 2070413.
RA Buerglin T. R.
RT The TEA domain: a novel, highly conserved DNA-binding motif
RL Cell 66:11-12 (1991).
RN [2]; RE0005292.
RX PUBMED: 7958896.
RA Chen Z., Friedrich G. A., Soriano P.
RT Transcriptional enhancer factor 1 disruption by a retroviral gene trap leads to heart defects and embryonic lethality in mice
RL Genes Dev. 8:2293-2301 (1994).
RN [3]; RE0005294.
RX PUBMED: 8441689.
RA Blatt C., DePamphilis M. L.
RT Striking homology between the mouse and human transcriptional enhancer factor-1 (TEF-1)
RL Nucleic Acids Res. 21:747-748 (1993).
RN [4]; RE0008662.
RX PUBMED: 8396764.
RA Shimizu N., Smith G., Izumo S.
RT Both a ubiquitous factor mTEF-1 and a distinct muscle-specific factor bind to the M-CAT motif of the myosin heavy chain beta gene.
RL Nucleic Acids Res. 21:4103-4110 (1993).
RN [5]; RE0017925.
RX PUBMED: 11751932.
RA Carlini L. E., Getz M. J., Strauch A. R., Kelm RJ J. r.
RT Cryptic MCAT enhancer regulation in fibroblasts and smooth muscle cells. Suppression of TEF-1 mediated activation by the single-stranded DNA-binding proteins, Pur alpha, Pur beta, and MSY1
RL J. Biol. Chem. 277:8682-8692 (2002).
RN [6]; RE0025059.
RX PUBMED: 11136726.
RA Gupta M., Kogut P., Davis F. J., Belaguli N. S., Schwartz R. J., Gupta M. P.
RT Physical interaction between the MADS box of serum response factor and the TEA/ATTS DNA-binding domain of transcription enhancer factor-1.
RL J. Biol. Chem. 276:10413-10422 (2001).
RN [7]; RE0072967.
RX PUBMED: 21376238.
RA Schlegelmilch K., Mohseni M., Kirak O., Pruszak J., Rodriguez J. R., Zhou D., Kreger B. T., Vasioukhin V., Avruch J., Brummelkamp T. R., Camargo F. D.
RT Yap1 acts downstream of alpha-catenin to control epidermal proliferation.
RL Cell 144:782-795 (2011).
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