AC T01692
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ID T01692
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DT 23.02.1996 (created); ewi.
DT 08.12.2009 (updated); jig.
CO Copyright (C), QIAGEN.
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FA T3R-beta1
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SY NR1A2; T3R-beta; T3R-beta1; thyroid hormone receptor beta; thyroid hormone receptor-beta1; TR.
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OS chick, Gallus gallus
OC eukaryota; animalia; metazoa; chordata; vertebrata; aves; neornithes; neognathae; galliformes; phasianidae
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GE G031658 THRB.
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CL C0002; CC (rec).
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SZ 369 AA; 42.1 kDa (cDNA) (calc.).
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SQ MSGYIPSYLDKDELCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYEGKCV
SQ IDKVTRNQCQECRFKKCIFVGMATDLVLDDSKRLAKRKLIEENREKRRREELQKTMGHKP
SQ EPTDEEWELIKIVTEAHVATNAQGSHWKQKRKFLPEDIGQAPIVNAPEGGKVDLEAFSQF
SQ TKIITPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLNG
SQ EMAVTRGQLKNGGLGVVSDAIFDLGMSLSSFNLDDTEVALLQAVLLMSSDRPGLVCVERI
SQ EKCQEGFLLAFEHYINYRKHHVAHFWPKLLMKVTDLRMIGACHASRFLHMKVECPTELFP
SQ PLFLEVFED
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SC Swiss-Prot#P68306-1
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FT 12 85 
SM00399; c4gold.
FT 12 89 
PS51030; NUCLEAR_REC_DBD_2.
FT 13 90 
PF00105; Zinc finger, C4 type (two domains).
FT 45 291 
PF00478; IMP dehydrogenase / GMP reductase domai.
FT 182 340 
SM00430; holi.
FT 185 366 
PF00104; Ligand-binding domain of nuclear hormon.
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SF splice variant: T3R-beta2;
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CP cerebellum: white matter, granule cells.
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FF sharply induced after E19 in brain;
FF may have a function in late, hormone-dependent glial and neuronal maturation [1];
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IN T01332 RXR-beta; mouse, Mus musculus.
IN T01334 RXR-beta; human, Homo sapiens.
IN T01349 RXR-beta; rat, Rattus norvegicus.
IN T08256 SRC-1A; human, Homo sapiens.
IN T08439 TIF2; mouse, Mus musculus.
IN T01355 TRAP; human, Homo sapiens.
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MX M02119 V$T3RBETA_Q6_01.
MX M00963 V$T3R_Q6.
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BS R01465.
BS R03942.
BS R03102.
BS R02595.
BS R00619.
BS R02694.
BS R02695.
BS R02696.
BS R03523.
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DR TRANSPATH: MO000025874.
DR EMBL: M65207;
DR EMBL: X17504;
DR UniProtKB: P68306-1;
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RN [1]; RE0000466.
RX PUBMED: 1991448.
RA Forrest D., Hallboeoek F., Persson H., Vennstroem B.
RT Distinct functions for thyroid hormone receptors alpha and beta in brain development indicated by differential expression of receptor genes
RL EMBO J. 10:269-275 (1991).
RN [2]; RE0003848.
RX PUBMED: 1970296.
RA Forrest D., Sjoeberg M., Vennstroem B.
RT Contrasting developmental and tissue-specific expression of alpha and beta thyroid hormone receptors
RL EMBO J. 9:1519-1528 (1990).
RN [3]; RE0003849.
RX PUBMED: 1707280.
RA Showers M. O., Darling D. S., Kieffer G. D., Chin W. W.
RT Isolation and characterization of a cDNA encoding a chicken beta thyroid hormone receptor
RL DNA Cell Biol. 10:211-221 (1991).
RN [4]; RE0047657.
RX PUBMED: 11435616.
RA Yang Z., Privalsky M. L.
RT Isoform-specific transcriptional regulation by thyroid hormone receptors: hormone-independent activation operates through a steroid receptor mode of co-activator interaction.
RL Mol. Endocrinol. 15:1170-1185 (2001).
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