AC T04355
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ID T04355
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DT 23.02.2001 (created); rio.
DT 07.04.2009 (updated); djp.
CO Copyright (C), QIAGEN.
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FA zhx1
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SY zinc finger homeobox protein 1.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G002245 ZHX1; HGNC: ZHX1.
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HO Vdx (hamster) T04266.
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CL C0006; homeo; 3.1.8.5.1.
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SF nearly identical to murine Zhx-1 T04356 and hamster Vdx T04266 [1];
SF physical interaction (in vitro and in vivo) with NF-YA T01804 [1];
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CP (adult:) highly expressed in heart, brain, pancreas, kidney, placenta and skeletal muscle, lower expressed in lung and liver [1].
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IN T19409 BS69; human, Homo sapiens.
IN T00133 c-Jun; human, Homo sapiens.
IN T08562 CREB1; human, Homo sapiens.
IN T05838 DEC1; human, Homo sapiens.
IN T27226 lyar; human, Homo sapiens.
IN T01804 NF-YA; human, Homo sapiens.
IN T08563 NF-YA; Mammalia.
IN T01806 p53; mouse, Mus musculus.
IN T34280 TDP43; human, Homo sapiens.
IN T15949 TRF1; human, Homo sapiens.
IN T19469 ZNF33b; human, Homo sapiens.
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DR TRANSPATH: MO000028213.
DR UniProtKB: Q9UKY1;
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RN [1]; RE0015796.
RX PUBMED: 10441475.
RA Yamada K., Printz R. L., Osawa H., Granner D. K.
RT Human ZHX1: cloning, chromosomal location, and interaction withtranscription factor NF-Y
RL Biochem. Biophys. Res. Commun. 261:614-621 (1999).
RN [2]; RE0027715.
RX PUBMED: 10571058.
RA Yamada K., Osawa H., Granner D. K.
RT Identification of proteins that interact with NF-YA.
RL FEBS Lett. 460:41-5 (1999).
RN [3]; RE0048055.
RX PUBMED: 15383276.
RA Goehler H., Lalowski M., Stelzl U., Waelter S., Stroedicke M., Worm U., Droege A., Lindenberg K. S., Knoblich M., Haenig C., Herbst M., Suopanki J., Scherzinger E., Abraham C., Bauer B., Hasenbank R., Fritzsche A., Ludewig A. H., Bussow K., Coleman S. H., Gutekunst C. A., Landwehrmeyer B. G., Lehrach H., Wanker E. E.
RT A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease.
RL Mol. Cell 15:853-865 (2004).
RN [4]; RE0063261.
RX PUBMED: 16169070.
RA Stelzl U., Worm U., Lalowski M., Haenig C., Brembeck F. H., Goehler H., Stroedicke M., Zenkner M., Schoenherr A., Koeppen S., Timm J., Mintzlaff S., Abraham C., Bock N., Kietzmann S., Goedde A., Toksoz E., Droege A., Krobitsch S., Korn B., Birchmeier W., Lehrach H., Wanker E. E.
RT A human protein-protein interaction network: a resource for annotating the proteome.
RL Cell 122:957-968 (2005).
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