AC T08891
XX
ID T08891
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DT 08.05.2006 (created); jag.
DT 14.02.2014 (updated); yre.
CO Copyright (C), QIAGEN.
XX
FA PSF-isoform1
XX
SY Polypyrimidine tract binding protein associated; POMP100; PSF; PSF-A; SFPQ; SFPQ-A; Splicing factor proline/glutamine rich; splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated).
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G018789 SFPQ; HGNC: SFPQ.
XX
CL C0066; NonO; 0.2.1.0.2.1.
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SZ 707 AA; 76.2 kDa (cDNA) (calc.).
XX
SQ MSRDRFRSRGGGGGGFHRRGGGGGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPI
SQ PPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPG
SQ VGSTPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQ
SQ AGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPRRGGGE
SQ PRGGRQHHPPYHQQHHQGPPPGGPGGRSEEKISDSEGFKANLSLLRRPGEKTYTQRCRLF
SQ VGNLPADITEDEFKRLFAKYGEPGEVFINKGKGFGFIKLESRALAEIAKAELDDTPMRGR
SQ QLRVRFATHAAALSVRNLSPYVSNELLEEAFSQFGPIERAVVIVDDRGRSTGKGIVEFAS
SQ KPAARKAFERCSEGVFLLTTTPRPVIVEPLEQLDDEDGLPEKLAQKNPMYQKERETPTRF
SQ AQHGTFEYEYSQRWKSLDEMEKQQREQVEKNMKDAKDKLESEMEDAYHEHQANLLRQDLM
SQ RRQEELRRMEELHNQEMQKRKEMQLRQEEERRRREEEMMIRQREMEDQMRRQREESYSRM
SQ GYMDPRERDMRMGGGGAMNMGDPYGSGGQKFPPLGGGGGIGYEANPGVPPATMSGSMMGS
SQ DMRTERFGQGGAGPVGGQGPRGMGPGTPAGYGRGREEYEGPNKKPRF
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SC translated from EMBL:BC051192
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FT 1 560 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 297 369 
PS50102; RRM.
FT 298 365 
SM00360; rrm1_1.
FT 299 364 
PF00076; RNA recognition motif. (a.k.a. RRM, RBD, or.
FT 371 452 
PS50102; RRM.
FT 372 448 
SM00360; rrm1_1.
FT 373 443 
PF00076; RNA recognition motif. (a.k.a. RRM, RBD, or.
FT 444 495 
PF08075; NOPS (NUC059) domain.
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IN T28742 BCLAF1; human, Homo sapiens.
IN T01661 PR A; human, Homo sapiens.
IN T00696 PR B; human, Homo sapiens.
IN T08348 RXR-alpha; mouse, Mus musculus.
IN T25617 sin3a; mouse, Mus musculus.
IN T08501 T3R-alpha; chick, Gallus gallus.
IN T34363 TRAP150; human, Homo sapiens.
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DR TRANSPATH: MO000081067.
DR EMBL: BC051192;
DR UniProtKB: P23246-1;
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RN [1]; RE0047677.
RX PUBMED: 11259580.
RA Mathur M., Tucker P. W., Samuels H. H.
RT PSF is a novel corepressor that mediates its effect through Sin3A and the DNA binding domain of nuclear hormone receptors.
RL Mol. Cell. Biol. 21:2298-2311 (2001).
RN [2]; RE0047842.
RX PUBMED: 15668243.
RA Dong X., Shylnova O., Challis J. R., Lye S. J.
RT Identification and characterization of the protein-associated splicing factor as a negative co-regulator of the progesterone receptor.
RL J. Biol. Chem. 280:13329-13340 (2005).
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