AC T09293
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ID T09293
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DT 04.09.2006 (created); kar.
DT 08.01.2016 (updated); sla.
CO Copyright (C), QIAGEN.
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FA Ngn-2
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SY Atoh4; Atonal protein homolog 4; Helix-loop-helix protein mATH-4A; Math4A; Neurog2; neurogenin 2; ngn-2; ngn2.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G018648 Neurog2.
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CL C0010; bHLH.
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SZ 263 AA; 28.2 kDa (cDNA) (calc.).
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SQ MFVKSETLELKEEEEVLMLLGSASPASATLTPMSSSADEEEDEELRRPGSARGQRGAEAE
SQ QGVQGSPASGAGGCRPGRLLGLMHECKRRPSRSRAVSRGAKTAETVQRIKKTRRLKANNR
SQ ERNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFAHNYIWALTETLRLADHCAGAGGL
SQ QGALFTEAVLLSPGAALGASGDSPSPPSSWSCTNSPASSSNSTSPYSCTLSPASPGSDVD
SQ YWQPPPPEKHRYAPHLPLARDCI
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SC translated from EMBL #U76207
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FT 110 165 PS50888; HLH.
FT 113 165 PF00010; Helix-loop-helix DNA-binding domain.
FT 118 170 SM00353; finulus.
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IN T00675 E12; rat, Rattus norvegicus.
IN T01786 E12; mouse, Mus musculus.
IN T01788 E47; mouse, Mus musculus.
IN T09295 MASH-1; mouse, Mus musculus.
IN T09293 Ngn-2; mouse, Mus musculus.
IN T09290 OLIG2; mouse, Mus musculus.
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MX M07609 V$NGN2_Q3.
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BS R70470.
BS R70471.
BS R70472.
BS R70511.
BS R70512.
BS R70473.
BS R70474.
BS R70475.
BS R70476.
BS R70477.
BS R70478.
BS R70513.
BS R70514.
BS R70515.
BS R70516.
BS R70520.
BS R70522.
BS R70523.
BS R70525.
BS R70526.
BS R70503.
BS R70504.
BS R70505.
BS R70509.
BS R70510.
BS R70506.
BS R70507.
BS R70508.
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DR TRANSPATH: MO000086218.
DR EMBL: U76207; MMU76207.
DR UniProtKB: P70447; NGN2_MOUSE.
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RN [1]; RE0035127.
RX PUBMED: 11502254.
RA Gowan K., Helms A. W., Hunsaker T. L., Collisson T., Ebert P. J., Odom R., Johnson J. E.
RT Crossinhibitory activities of Ngn1 and Math1 allow specification of distinct dorsal interneurons.
RL Neuron 31:219-232 (2001).
RN [2]; RE0048183.
RX PUBMED: 15655114.
RA Lee S. K., Lee B., Ruiz E. C., Pfaff S. L.
RT Olig2 and Ngn2 function in opposition to modulate gene expression in motor neuron progenitor cells.
RL Genes Dev. 19:282-294 (2005).
RN [3]; RE0048188.
RX PUBMED: 8948587.
RA Gradwohl G., Fode C., Guillemot F.
RT Restricted expression of a novel murine atonal-related bHLH protein in undifferentiated neural precursors.
RL Dev. Biol. 180:227-241 (1996).
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