AC T01788
XX
ID T01788
XX
DT 02.05.1996 (created); ewi.
DT 30.07.2014 (updated); spk.
CO Copyright (C), QIAGEN.
XX
FA E47
XX
SY E2A; E47.
XX
OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
XX
GE G005705 Tcf3.
XX
CL C0010; bHLH; 1.2.1.0.1.2.
XX
SZ 648 AA; 67.4 kDa (cDNA) (calc.).
XX
SQ MMNQSQRMAPVGSDKELSDLLDFSMMFPLPVANGKSRPASLGGTQFAGSGLEDRPSSGSW
SQ GSSDQNSSSFDPSRTYSEGAHFSDSHSSLPPSTFLGAGLGGKGSERNAYATFGRDTSVGT
SQ LSQAGFLPGELSLSSPGPLSPSGIKSSSQYYPSFPSNPRRRAADGGLDTQPKKVRKVPPG
SQ LPSSVYPPSSGDSYSRDAAAYPSAKTPSSAYPSPFYVADGSLHPSAELWSTPSQVGFGPM
SQ LGDGSSPLPLAPGSSSVGSGTFGGLQQQDRMGYQLHGSEVNGSLPAVSSFSAAPGTYSGT
SQ SGHTPPVSGAAAESLLGTRGTTASSSGDALGKALASIYSPDHSSNNFSPSPSTPVGSPQG
SQ LPGTSQWPRAGAPSALSPNYDAGLHGLSKMEDRLDEAIHVLRSHAVGTASDLHGLLPGHG
SQ ALTTSFTGPMSLGGRHAGLVGGSHPEEGLTSGASLLHNHASLPSQPSSLPDLSQRPPDSY
SQ SGLGRAGTTAGASEIKREEKEDEEIASVADAEEDKKDLKVPRTRTSSTDEVLSLEEKDLR
SQ DRERRMANNARERVRVRDINEAFRELGRMCQLHLKSDKAQTKLLILQQAVQVILGLEQQV
SQ RERNLNPKAACLKRREEEKVSGVVGDPQLALSAAHPGLGEAHNPAGHL
XX
SC Swiss-Prot#P15806-2
XX
FF functional redundancy with other products of the E2A and E2-2 genes [2];
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IN T00003 AS-C T3; fruit fly, Drosophila melanogaster.
IN T16150 BRG1; mouse, Mus musculus.
IN T27826 Dnmt1; mouse, Mus musculus.
IN T00204 E12; human, Homo sapiens.
IN T00403 Id1; mouse, Mus musculus.
IN T00404 Id2; mouse, Mus musculus.
IN T01212 Id2; human, Homo sapiens.
IN T10004 Id2; mouse, Mus musculus.
IN T00367 Id3; mouse, Mus musculus.
IN T09198 Id3; mouse, Mus musculus.
IN T18839 Mi2-BETA; mouse, Mus musculus.
IN T00526 MyoD; mouse, Mus musculus.
IN T09293 Ngn-2; mouse, Mus musculus.
IN T21599 nucleolin; mouse, Mus musculus.
IN T09290 OLIG2; mouse, Mus musculus.
IN T26600 p54NRB; mouse, Mus musculus.
IN T14136 PC4; mouse, Mus musculus.
IN T00790 Tal1-PP42; human, Homo sapiens.
XX
MX M00693 V$E12_Q6.
MX M00804 V$E2A_Q2.
MX M00973 V$E2A_Q6.
MX M02088 V$E2A_Q6_01.
MX M07353 V$E2A_Q6_02.
MX M00002 V$E47_01.
MX M00071 V$E47_02.
MX M01034 V$EBOX_Q6_01.
MX M00222 V$HAND1E47_01.
MX M00929 V$MYOD_Q6_01.
MX M00066 V$TAL1ALPHAE47_01.
MX M00065 V$TAL1BETAE47_01.
XX
BS R16664.
BS R16665.
BS R16668.
BS R16669.
BS R16670.
BS R04764.
BS R10079.
BS R00019.
BS R13322.
BS R35391.
BS R13330.
BS R26276.
BS R00881.
BS R00223.
BS R00909.
XX
DR TRANSPATH: MO000025925.
DR TRANSCOMPEL: C00374.
DR TRANSCOMPEL: C00376.
DR EMBL: X17500;
DR UniProtKB: P15806-2;
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RN [1]; RE0001998.
RX PUBMED: 2181401.
RA Walker M. D., Park C. W., Rosen A., Aronheim A.
RT A cDNA from a mouse pancreatic beta cell encoding a putative transcription factor of the insulin gene
RL Nucleic Acids Res. 18:1159-1166 (1990).
RN [2]; RE0004017.
RX PUBMED: 1465450.
RA Zhuang Y., Kim C. G., Bartelmez S., Cheng P., Groudine M., Weintraub H.
RT Helix-loop-helix transcription factors E12 and E47 are not essential for skeletal or cardiac myogenesis, erythrpoiesis, chondrogenesis or neurogenesis
RL Proc. Natl. Acad. Sci. USA 89:12132-12136 (1992).
RN [3]; RE0004026.
RX PUBMED: 8112613.
RA Kajimoto Y., Kawamori R., Umayahara Y., Watada H., Iwama N., Morishima T., Yamasaki Y., Kamada T.
RT Identification of amino-acid polymorphism within the leucine zipper motif of mouse transcription factor A1
RL Gene 139:247-249 (1994).
RN [4]; RE0012509.
RX PUBMED: 8759016.
RA Loveys D. A., Streiff M. B., Kato G. J.
RT E2A basic-helix-loop-helix transcription factors are negatively regulated by serum growth factors and by the ld3 protein
RL Nucleic Acids Res. 24:2813-2820 (1996).
RN [5]; RE0048183.
RX PUBMED: 15655114.
RA Lee S. K., Lee B., Ruiz E. C., Pfaff S. L.
RT Olig2 and Ngn2 function in opposition to modulate gene expression in motor neuron progenitor cells.
RL Genes Dev. 19:282-294 (2005).
RN [6]; RE0048980.
RX PUBMED: 9242638.
RA Langlands K., Yin X., Anand G., Prochownik E. V.
RT Differential interactions of Id proteins with basic-helix-loop-helix transcription factors.
RL J. Biol. Chem. 272:19785-19793 (1997).
XX
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