AC T00675
XX
ID T00675
XX
DT 09.12.1992 (created); ewi.
DT 29.07.2014 (updated); yre.
CO Copyright (C), QIAGEN.
XX
FA E12
XX
SY E12; E2A; Pan-2; PAN2; Tcfe2a; transcription factor E2a.
XX
OS rat, Rattus norvegicus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
XX
GE G009197 Tcf3.
XX
CL C0010; bHLH; 1.2.1.0.1.1.
XX
SZ 649 AA; 67.6 kDa (cDNA) (calc.).
XX
SQ MMNQSQRMAPVGSDKELSDLLDFSMMFPLPVANGKGRPASLAGTQFAGSGLEDRPSSESW
SQ GNSEQNSSSFDPSRAYSEGAHFSDSHSSLPPSTFLGAGLGGKGSERNAYATFGRDTSVGT
SQ LSQAGFLPGELGLSSPGPLSPSGVKSSSQYYTSFPSNPRRRAADGGLDTQPKKVRKVPPG
SQ LPSSVYPSSSGDNYSRDATAYPSAKTPSSAYPSPFYVADGSLHPSAELWSPPGQVGFGPM
SQ LGDGSAPLPLAPGSSSVSSGAFGGLQQQDRMGYQLHGSEVNGTLPAVSSFSAAPGTYSGT
SQ SGHTPPVSGADSLLGTRGTTASSSGDALGKALASIYSPDHSSNNFSPSPSTPVGSPQGLP
SQ GTSQWPRAGAPSALSPNYDAGLHGLSKMEDRLDEAIHVLRSHAVGTASELHGLLPGHSTL
SQ TTSFAGPMSLGGRHAGLVSGSHPEDGLTSGASLLHNHASLPSQPSSLPDLSQRPPDSFSG
SQ LGRAGVTAGASEIKREEKEDEEVTSVADAEEDKKDLKVPRTRTSPDEDEDDLLPPEQKAE
SQ REKERRVANNARERLRVRDINEAFKELGRMCQLHLSTEKPQTKLLILHQAVAVILSLEQQ
SQ VRERNLNPKAACLKRREEEKVSGVVGDPQLALSAAHPGLGEAHNPAGHL
XX
SC Swiss-Prot#P21677-1
XX
FT 542 598 
PS50888; HLH.
FT 545 598 
PF00010; Helix-loop-helix DNA-binding domain.
FT 550 603 
SM00353; finulus.
XX
IN T00036 AP-4; human, Homo sapiens.
IN T00003 AS-C T3; fruit fly, Drosophila melanogaster.
IN T00207 E47; human, Homo sapiens.
IN T00403 Id1; mouse, Mus musculus.
IN T01811 Id3; rat, Rattus norvegicus.
IN T00484 MASH-1; rat, Rattus norvegicus.
IN T01619 MASH-1; mouse, Mus musculus.
IN T09295 MASH-1; mouse, Mus musculus.
IN T00485 MASH-2; rat, Rattus norvegicus.
IN T00512 MRF4; rat, Rattus norvegicus.
IN T00521 Myf-5; human, Homo sapiens.
IN T00526 MyoD; mouse, Mus musculus.
IN T00528 myogenin; mouse, Mus musculus.
IN T09293 Ngn-2; mouse, Mus musculus.
IN T00926 SUM-1; sea urchin, Lytechinus variegatus.
IN T26764 Twist; rat, Rattus norvegicus.
XX
MX M00693 V$E12_Q6.
MX M00804 V$E2A_Q2.
MX M00973 V$E2A_Q6.
MX M02088 V$E2A_Q6_01.
MX M07353 V$E2A_Q6_02.
MX M00002 V$E47_01.
MX M00071 V$E47_02.
MX M01034 V$EBOX_Q6_01.
MX M00222 V$HAND1E47_01.
MX M00929 V$MYOD_Q6_01.
MX M00066 V$TAL1ALPHAE47_01.
MX M00065 V$TAL1BETAE47_01.
XX
BS R04046.
BS R00223.
BS R35977.
BS R35978.
BS R35992.
XX
DR TRANSPATH: MO000025099.
DR EMBL: S77532;
DR UniProtKB: P21677-1;
XX
RN [1]; RE0000661.
RX PUBMED: 2200736.
RA Nelson C., Shen L.-P., Meister A., Fodor E., Rutter W. J.
RT Pan: a transcriptional regulator that binds chymotrypsin, insulin, and AP-4 enhancer motifs
RL Genes Dev. 4:1035-1043 (1990).
RN [2]; RE0002248.
RX PUBMED: 1766666.
RA Metz R., Ziff E.
RT The helix-loop-helix protein rE12 and the C/EBP-related factor rNFIL-6 bind to neighboring sites within the c-fos serum response element
RL Oncogene 6:2165-2178 (1991).
RN [3]; RE0048188.
RX PUBMED: 8948587.
RA Gradwohl G., Fode C., Guillemot F.
RT Restricted expression of a novel murine atonal-related bHLH protein in undifferentiated neural precursors.
RL Dev. Biol. 180:227-241 (1996).
RN [4]; RE0049050.
RX PUBMED: 10567574.
RA Thomas M. K., Yao K. M., Tenser M. S., Wong G. G., Habener J. F.
RT Bridge-1, a novel PDZ-domain coactivator of E2A-mediated regulation of insulin gene transcription.
RL Mol. Cell. Biol. 19:8492-8504 (1999).
XX
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