AC T01619
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ID T01619
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DT 29.01.1996 (created); ewi.
DT 24.05.2013 (updated); uat.
CO Copyright (C), QIAGEN.
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FA MASH-1
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SY ASH-1; mammalian achaete-scute homolog 1; MASH-1.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G001829 Ascl1.
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CL C0010; bHLH; 1.2.2.2.1.
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CP nervous system: neuroepithelial and neural crest cells, neural precursors [1]; low in adult brain [2]; neural tube [4] [1] [2] [4]; expression is restricted to the midbrain-hindbrain junction, expression in the developing spinal cord [6].
CN bone marrow, eyes, heart, kidney, lung, muscle, ovary, pancreas, spinal cord, spleen, testis, thymus [2].
EX epithelium of respiratory region of nasal cavity,,,Theiler Stage 21; none; RNA-in situ hybridization (not further specified); RNA (undefined); [6].
EX epithelium of respiratory region of nasal cavity,,,Theiler Stage 23; none; RNA-in situ hybridization (not further specified); RNA (undefined); [6].
EX neural layer of retina,,,Theiler Stage 23; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [6].
EX neural tube,,,Theiler Stage 17; detectable; RNA-in situ hybridization (non-radioactive); RNA (undefined); [4].
EX olfactory epithelium,,,Theiler Stage 21; high; RNA-in situ hybridization (not further specified); RNA (undefined); [6].
EX olfactory epithelium,,,Theiler Stage 23; high; RNA-in situ hybridization (not further specified); RNA (undefined); [6].
EX outer nuclear layer of retina,,,Theiler Stage 25; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [6].
EX spinal cord,,,Theiler Stage 19; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [6].
EX spinal cord,,,Theiler Stage 21; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [6].
EX ventricular layer of mesencephalon,dopaminergic neuron,,Theiler Stage 19; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [6].
EX ventricular layer of the cerebral cortex,,,Theiler Stage 21; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [6].
EX vomeronasal organ,,,Theiler Stage 21; high; RNA-in situ hybridization (not further specified); RNA (undefined); [6].
EX vomeronasal organ,,,Theiler Stage 23; high; RNA-in situ hybridization (not further specified); RNA (undefined); [6].
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FF essential for normal development of olfactory epithelium, sympathetic, parasympathetic, and enteric ganglia beyond neural precursor stage [1];
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IN T02327 DEC1; mouse, Mus musculus.
IN T00204 E12; human, Homo sapiens.
IN T00675 E12; rat, Rattus norvegicus.
IN T01786 E12; mouse, Mus musculus.
IN T01787 E12; clawed frog, Xenopus laevis.
IN T01503 HTF4; human, Homo sapiens.
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MX M00973 V$E2A_Q6.
MX M01034 V$EBOX_Q6_01.
MX M03877 V$MASH1_Q6.
MX M07422 V$MASH1_Q6_01.
MX M08820 V$MASH1_Q6_02.
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BS R56190.
BS R56167.
BS R56186.
BS R00242.
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DR TRANSPATH: MO000025807.
DR UniProtKB: Q02067;
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RN [1]; RE0003629.
RX PUBMED: 8221886.
RA Guillemot F., Lo L.-C., Johnson J. E., Auerbach A., Anderson D. J., Joyner A. L.
RT Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neurons
RL Cell 75:463-476 (1993).
RN [2]; RE0003630.
RX PUBMED: 8424959.
RA Franco del Amo F., Gendron-Maguire M., Swiatek P.J., Gridley T.
RT Cloning, sequencing and expression of the mouse mammalian achaete-scute homolog 1 (MASH1)
RL Biochim. Biophys. Acta 1171:323-327 (1993).
RN [3]; RE0006798.
RX PUBMED: 7589808.
RA Li L., Cserjesi P., Olson E. N.
RT Dermo-1: A novel twist-related bHLH protein expressed in the developing dermis
RL Dev. Biol. 172:280-292 (1995).
RN [4]; RE0035127.
RX PUBMED: 11502254.
RA Gowan K., Helms A. W., Hunsaker T. L., Collisson T., Ebert P. J., Odom R., Johnson J. E.
RT Crossinhibitory activities of Ngn1 and Math1 allow specification of distinct dorsal interneurons.
RL Neuron 31:219-232 (2001).
RN [5]; RE0049091.
RX PUBMED: 12200424.
RA Heng J. I., Tan S. S.
RT Cloning and characterization of GRIPE, a novel interacting partner of the transcription factor E12 in developing mouse forebrain.
RL J. Biol. Chem. 277:43152-43159 (2002).
RN [6]; RE0035294.
RX PUBMED: 10704856.
RA Cohen D. R., Cheng C. W., Cheng S. H., Hui C. C.
RT Expression of two novel mouse Iroquois homeobox genes during neurogenesis.
RL Mech. Dev. 91:317-321 (2000).
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