AC T01787
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ID T01787
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DT 02.05.1996 (created); ewi.
DT 09.05.2008 (updated); mkl.
CO Copyright (C), QIAGEN.
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FA E12
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SY E12; E2A; XE12.
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OS clawed frog, Xenopus laevis
OC eukaryota; animalia; metazoa; chordata; vertebrata; amphibia; lissamphibia; anura; archeobatrachia; pipoidea; pipidae
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CL C0010; bHLH.
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SZ 658 AA; 70.1 kDa (cDNA) (calc.).
XX
SQ MNQQQRMTAVGTDKELSDLLDFSMMFPLPVANGKTRPTTLASTQFGGGSGLEERTGSAPW
SQ GTEDHNGSTFDQGRGYGDGTHYGEHRELPSHEGNLSAPFLASGLVGKNDRPPYSTFGRDS
SQ GMTMNQTGFLSGDLAMNSPSALSPNAGKAGSQYYTYPNNSRRRPGDSNLDAQPKKVRKVP
SQ PGLPSSVYPANSGDEYCGDRGSYASTKTPNSVYPGAFYMADGLHSSDIWASSGGIGQGGY
SQ SSVLNSSQSSVSQTTGFSSLHPHERMGFPMHSGEVNPSVTSSFSSTPAQYGVSSHTPPIS
SQ TGDTIIGNRGTATGSSGDALGKALASIYSPDHSSTNFSSTPSTPVGSPQGITGSGQWPRA
SQ NGPGALSPSYDGTLHTLQNKMEDRLDEAIHVLRSHAVGQTGALPGGHDDIHSLLSATASV
SQ LGSGFPAAVLSLANRHSMLNSHTEEALPSASNMLHSQVTVPAQPGSLPDLTRPQDSYSGL
SQ PGLGRAIPPGRVPDIKRESKEDEENRSVADLSDDEKKESKPQRSRTRCSINSQDEDEDED
SQ DDNLPPEQKAEREKERRVANNARERLRVKDINEAFKELGRMCQLHLNSEKPQTKLLILHQ
SQ AVSVILSLEQQVRERNLNPKAACLKRREEEKVSGVDPQMGLSGGHPGVGDSHNPVGHM
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SC conceptually translated from EMBL/GenBank/DDBJ #X66959
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FT 107 449 PF00478; IMP dehydrogenase / GMP reductase domain.
FT 553 609 PS50888; HLH.
FT 556 609 PF00010; Helix-loop-helix DNA-binding domain.
FT 561 614 SM00353; finulus.
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IN T00036 AP-4; human, Homo sapiens.
IN T00003 AS-C T3; fruit fly, Drosophila melanogaster.
IN T00207 E47; human, Homo sapiens.
IN T00403 Id1; mouse, Mus musculus.
IN T00484 MASH-1; rat, Rattus norvegicus.
IN T01619 MASH-1; mouse, Mus musculus.
IN T00485 MASH-2; rat, Rattus norvegicus.
IN T00512 MRF4; rat, Rattus norvegicus.
IN T00521 Myf-5; human, Homo sapiens.
IN T00526 MyoD; mouse, Mus musculus.
IN T00528 myogenin; mouse, Mus musculus.
IN T00926 SUM-1; sea urchin, Lytechinus variegatus.
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MX M00693 V$E12_Q6.
MX M00973 V$E2A_Q6.
MX M02088 V$E2A_Q6_01.
MX M07353 V$E2A_Q6_02.
MX M01034 V$EBOX_Q6_01.
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BS R04046.
BS R00223.
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DR TRANSPATH: MO000025924.
DR EMBL: X66959;
DR UniProtKB: Q01978;
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RN [1]; RE0003224.
RX PUBMED: 1322293.
RA Rashbass J., Taylor M. V., Gurdon J. B.
RT The DNA-binding protein E12 co-operates with XMyoD in the activation of muscle-specific gene expression in Xenopus embryos
RL EMBO J. 11:2981-2990 (1992).
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