AC T00484
XX
ID T00484
XX
DT 20.10.1992 (created); ewi.
DT 06.08.2015 (updated); sup.
CO Copyright (C), QIAGEN.
XX
FA MASH-1
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SY ASH-1; mammalian achaete-scute homolog 1; MASH-1.
XX
OS rat, Rattus norvegicus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
XX
GE G009145 Ascl1.
XX
CL C0010; bHLH.
XX
SZ 233 AA; 25.0 kDa (cDNA) (calc.).
XX
SQ MESSGKMESGAGQQPQPPQPFLPPAACFFATAAAAAAAAAAAAAQSAQQQQQQQAPQQQA
SQ PQLSPVADGQPSGGGHKSAAKQVKRQRSSSPELMRCKRRLNFSGFGYSLPQQQPAAVARR
SQ NERERNRVKLVNLGFATLREHVPNGAANKKMSKVETLRSAVEYIRALQQLLDEHDAVSAA
SQ FQAGVLSPTISPNYSNDLNSMAGSPVSSYSSDEGSYDPLSPEEQELLDFTNWF
XX
SC Swiss-Prot#P19359
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FT 84 168 
PS50888; HLH.
FT 118 168 
PF00010; Helix-loop-helix DNA-binding domain.
FT 121 173 
SM00353; finulus.
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CP nervous system: neuroepithelial and neural crest cells.
XX
IN T00204 E12; human, Homo sapiens.
IN T00675 E12; rat, Rattus norvegicus.
IN T01787 E12; clawed frog, Xenopus laevis.
IN T01652 HES-5; rat, Rattus norvegicus.
IN T01790 HTF4alpha; rat, Rattus norvegicus.
IN T01791 HTF4beta; rat, Rattus norvegicus.
IN T01789 HTF4gamma; rat, Rattus norvegicus.
IN T01427 p300; human, Homo sapiens.
XX
MX M00973 V$E2A_Q6.
MX M01034 V$EBOX_Q6_01.
MX M03877 V$MASH1_Q6.
MX M07422 V$MASH1_Q6_01.
MX M08820 V$MASH1_Q6_02.
XX
BS R00242.
BS R68639.
BS R68640.
BS R69108.
XX
DR TRANSPATH: MO000024961.
DR EMBL: X53725;
DR UniProtKB: P19359;
XX
RN [1]; RE0000712.
RX PUBMED: 1909283.
RA Lo L.-C., Johnson J. E., Wuenschell C. W., Saito T., Anderson D. J.
RT Mammalian achaete-scute homolog 1 is transiently expressed by spatially restricted subsets of early neuroepithelial and neural crest cells
RL Genes Dev. 5:1524-1537 (1991).
RN [2]; RE0002436.
RX PUBMED: 1314394.
RA Johnson J. E., Birren S. J., Saito T., Anderson D. J.
RT DNA binding and transcriptional regulatory activity of mammalian achaete-scute homologous (MASH) proteins revealed by interaction with a muscle-specific enhancer
RL Proc. Natl. Acad. Sci. USA 89:3596-3600 (1992).
RN [3]; RE0003628.
RX PUBMED: 8422988.
RA Klein E. S., Simmons D. M., Swanson L. W., Rosenfeld M. G.
RT Tissue-specific RNA splicing generates an ankyrin-like domain that affects the dimerization and DNA-binding properties of a bHLH protein
RL Genes Dev. 7:55-71 (1993).
XX
//