AC T01791
XX
ID T01791
XX
DT 03.05.1996 (created); ewi.
DT 26.10.2006 (updated); ili.
CO Copyright (C), QIAGEN.
XX
FA HTF4beta
XX
SY salivary-specific CRE-binding protein beta; SCBP; TCF12; transcription factor 12.
XX
OS rat, Rattus norvegicus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
XX
GE G014506 Tcf12.
XX
CL C0010; bHLH.
XX
SZ 706 AA; 75.7 kDa (cDNA) (calc.).
XX
SQ MNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGMDERGGTTSW
SQ GTSGQPSPSYDSSRGFTDSPHYSDHLNDSRLGTHEGLSPTPFMNSNLIGKTSERGSFSLY
SQ SRDCGLSGCQSSLLRQDLGLGSPAQLSSSGKPGTPYYSSSATSSRRRPLHDSVALDPLQA
SQ KKVRKVPPGLPSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHSSSDLWSS
SQ SNGMSQPGFGGILGTSTSHMSQSSSYGSLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRG
SQ STSSSPYVAASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYSPDHTSSSFPSNP
SQ STPVGSPSPLTAGTSQWPRAGGQAPSSPSYENSLHSLKNRVEQQLHEHLQDAMSFLKDVC
SQ ESRMEDRLDRLDDAIHVLRNHAVGPSTSLPTSHSDIHSLLGPSHNAPIGNLNSNYGGSSL
SQ VTNSRSASMVGTHREDSVSLNGNHSVLSSTVAASNTELNHKTPESFRGGVQNQSGSVVPN
SQ EIKTENKEKDENLHEPPSSDDMKSDDESSQKDIKVSSRGRTSSTNEDEDLNPEQKIEREK
SQ ERRMANNARERLRVRDINEAFKELGRMCQLHLKSEKPQTKLLILHQAVAVILSLEQQVRE
SQ RNLNPKAACLKRREEEKVSAASAEPPTTLPGTHPGLSETTNPMGHL
XX
SC conceptually translated from EMBL/GenBank/DDBJ #L09656, #S53920 and #S53913
XX
FT 117 638 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 600 655 
PS50888; HLH.
FT 602 655 
PF00010; Helix-loop-helix DNA-binding domain.
FT 607 660 
SM00353; finulus.
XX
SF two splice variants are SCBPgamma and SCBPalpha [2];
XX
CP ubiquitous [1].
XX
FF weaker activator than SCBPgamma, responding to enhanced cAMP levels [2];
XX
IN T01789 HTF4gamma; rat, Rattus norvegicus.
IN T00484 MASH-1; rat, Rattus norvegicus.
IN T00485 MASH-2; rat, Rattus norvegicus.
IN T00512 MRF4; rat, Rattus norvegicus.
IN T00526 MyoD; mouse, Mus musculus.
XX
MX M00973 V$E2A_Q6.
MX M01034 V$EBOX_Q6_01.
MX M00698 V$HEB_Q6.
MX M02018 V$HTF4_Q2.
XX
DR TRANSPATH: MO000025928.
DR EMBL: S53913;
DR EMBL: S53921;
DR UniProtKB: P51514-2; HTF4_RAT.
XX
RN [1]; RE0003628.
RX PUBMED: 8422988.
RA Klein E. S., Simmons D. M., Swanson L. W., Rosenfeld M. G.
RT Tissue-specific RNA splicing generates an ankyrin-like domain that affects the dimerization and DNA-binding properties of a bHLH protein
RL Genes Dev. 7:55-71 (1993).
RN [2]; RE0003729.
RX PUBMED: 7683670.
RA Lin H. H., Li W. Y., Ann D. K.
RT The helix-loop-helix proteins (salivary-specific cAMP response element-binding proteins) can modulate cAMP-inducible RP4 gene expression in salivary cells
RL J. Biol. Chem. 268:10214-10220 (1993).
XX
//