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TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T00485 XX ID T00485 XX DT 20.10.1992 (created); ewi. DT 22.02.2005 (updated); elf. CO Copyright (C), QIAGEN. XX FA MASH-2 XX SY achaete-scute complex homolog-like 2 (Drosophila); ASCL2; ASH-2; mammalian achaete-scute homolog 2; MASH-2. XX OS rat, Rattus norvegicus OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae XX GE G014465 Ascl2. XX CL C0010; bHLH. XX SZ 260 AA; 27.7 kDa (calc.), 27.7 kDa XX SQ MESHFNWYGVPRLQKASDACPRESCSSALPEAREGANVHFPPHPVPREHFSCGAPKPVAG SQ APALNASLMDGGALPRLVPTSSGVAGACTARRRPPSPELLRCSRRRRSGATEASSSSAAV SQ ARRNERERNRVKLVNLGFQALRQHVPHGGANKKLSKVETLRSAVEYIRALQRLLAEHDAV SQ RAALSGGLLTPATRPSDVCTQPSASPASASLSCTSTSPDRLGCSEPASPRSAYSSEDSSC SQ EGETYPMGQMFDFSNWLGGY XX SC Swiss-Prot#P19360 XX FT 104 171 PS50888; HLH. FT 121 171 PF00010; Helix-loop-helix DNA-binding domain. FT 124 176 SM00353; finulus. XX IN T00204 E12; human, Homo sapiens. IN T00675 E12; rat, Rattus norvegicus. IN T01787 E12; clawed frog, Xenopus laevis. IN T01503 HTF4; human, Homo sapiens. IN T01790 HTF4alpha; rat, Rattus norvegicus. IN T01791 HTF4beta; rat, Rattus norvegicus. IN T01789 HTF4gamma; rat, Rattus norvegicus. XX MX M00973 V$E2A_Q6. MX M01034 V$EBOX_Q6_01. XX BS R00242. XX DR TRANSPATH: MO000024962. DR EMBL: X53724; DR UniProtKB: P19360; XX RN [1]; RE0002436. RX PUBMED: 1314394. RA Johnson J. E., Birren S. J., Saito T., Anderson D. J. RT DNA binding and transcriptional regulatory activity of mammalian achaete-scute homologous (MASH) proteins revealed by interaction with a muscle-specific enhancer RL Proc. Natl. Acad. Sci. USA 89:3596-3600 (1992). RN [2]; RE0003628. RX PUBMED: 8422988. RA Klein E. S., Simmons D. M., Swanson L. W., Rosenfeld M. G. RT Tissue-specific RNA splicing generates an ankyrin-like domain that affects the dimerization and DNA-binding properties of a bHLH protein RL Genes Dev. 7:55-71 (1993). XX //