AC T00485
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ID T00485
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DT 20.10.1992 (created); ewi.
DT 22.02.2005 (updated); elf.
CO Copyright (C), QIAGEN.
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FA MASH-2
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SY achaete-scute complex homolog-like 2 (Drosophila); ASCL2; ASH-2; mammalian achaete-scute homolog 2; MASH-2.
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OS rat, Rattus norvegicus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G014465 Ascl2.
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CL C0010; bHLH.
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SZ 260 AA; 27.7 kDa (calc.), 27.7 kDa
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SQ MESHFNWYGVPRLQKASDACPRESCSSALPEAREGANVHFPPHPVPREHFSCGAPKPVAG
SQ APALNASLMDGGALPRLVPTSSGVAGACTARRRPPSPELLRCSRRRRSGATEASSSSAAV
SQ ARRNERERNRVKLVNLGFQALRQHVPHGGANKKLSKVETLRSAVEYIRALQRLLAEHDAV
SQ RAALSGGLLTPATRPSDVCTQPSASPASASLSCTSTSPDRLGCSEPASPRSAYSSEDSSC
SQ EGETYPMGQMFDFSNWLGGY
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SC Swiss-Prot#P19360
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FT 104 171 
PS50888; HLH.
FT 121 171 
PF00010; Helix-loop-helix DNA-binding domain.
FT 124 176 
SM00353; finulus.
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IN T00204 E12; human, Homo sapiens.
IN T00675 E12; rat, Rattus norvegicus.
IN T01787 E12; clawed frog, Xenopus laevis.
IN T01503 HTF4; human, Homo sapiens.
IN T01790 HTF4alpha; rat, Rattus norvegicus.
IN T01791 HTF4beta; rat, Rattus norvegicus.
IN T01789 HTF4gamma; rat, Rattus norvegicus.
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MX M00973 V$E2A_Q6.
MX M01034 V$EBOX_Q6_01.
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BS R00242.
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DR TRANSPATH: MO000024962.
DR EMBL: X53724;
DR UniProtKB: P19360;
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RN [1]; RE0002436.
RX PUBMED: 1314394.
RA Johnson J. E., Birren S. J., Saito T., Anderson D. J.
RT DNA binding and transcriptional regulatory activity of mammalian achaete-scute homologous (MASH) proteins revealed by interaction with a muscle-specific enhancer
RL Proc. Natl. Acad. Sci. USA 89:3596-3600 (1992).
RN [2]; RE0003628.
RX PUBMED: 8422988.
RA Klein E. S., Simmons D. M., Swanson L. W., Rosenfeld M. G.
RT Tissue-specific RNA splicing generates an ankyrin-like domain that affects the dimerization and DNA-binding properties of a bHLH protein
RL Genes Dev. 7:55-71 (1993).
XX
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