AC T10332
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ID T10332
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DT 10.03.2005 (created); nvo.
DT 19.02.2015 (updated); ros.
CO Copyright (C), QIAGEN.
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FA ipf1
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SY IDX-1; insulin promoter factor 1; IPF-1; ISLET/duodenum homeobox-1; pancreas/duodenum homeobox 1; pancreas/duodenum homeobox-1; Pdx1; somatostatin transactivating factor 1; somatostatin transactivating factor-1; STF-1; STF1.
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OS Mammalia
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia
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IN T02056 ATF-2-isoform1; mouse, Mus musculus.
IN T08343 HDAC1; human, Homo sapiens.
IN T04109 hdac2-isoform1; human, Homo sapiens.
IN T33294 Ku70; mouse, Mus musculus.
IN T33293 Ku80; mouse, Mus musculus.
IN T08226 MafA; mouse, Mus musculus.
IN T09908 MafA; mouse, Mus musculus.
IN T23091 p300; Mammalia.
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MX M01233 V$IPF1_01.
MX M01234 V$IPF1_02.
MX M01235 V$IPF1_03.
MX M01236 V$IPF1_04.
MX M01255 V$IPF1_05.
MX M01438 V$IPF1_06.
MX M00436 V$IPF1_Q4.
MX M01013 V$IPF1_Q4_01.
MX M02096 V$IPF1_Q5.
MX M04614 V$IPF1_Q5_01.
MX M01275 V$IPF1_Q6.
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BS R59926.
BS R10024.
BS R10025.
BS R19189.
BS R02709.
BS R64568.
BS R21510.
BS R65192.
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DR TRANSPATH: MO000047576.
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RN [1]; RE0014615.
RX PUBMED: 9710595.
RA Swift G. H., Liu Y., Rose S. D., Bischof L. J., Steelman S., Buchberg A. M., Wright C. V., MacDonald R. J.
RT An endocrine-exocrine switch in the activity of the pancreatic homeodomain protein PDX1 through formation of a trimeric complex with PBX1b and MRG1 (MEIS2)
RL Mol. Cell. Biol. 18:5109-5120 (1998).
RN [2]; RE0016247.
RX PUBMED: 10629047.
RA Ohneda K., Mirmira R. G., Wang J., Johnson J. D., German M. S.
RT The homeodomain of PDX-1 mediates multiple protein-protein interactions in the formation of a transcriptional activation complex on the insulin promoter.
RL Mol. Cell. Biol. 20:900-911 (2000).
RN [3]; RE0024057.
RX PUBMED: 9933599.
RA Goudet G., Delhalle S., Biemar F., Martial J. A., Peers B.
RT Functional and cooperative interactions between the homeodomain PDX1, Pbx, and Prep1 factors on the somatostatin promoter.
RL J. Biol. Chem. 274:4067-4073 (1999).
RN [4]; RE0031600.
RX PUBMED: 14748724.
RA Tarling E., Salter A., Bennett A.
RT Transcriptional regulation of human SREBP-1c (sterol-regulatory-element-binding protein-1c): a key regulator of lipogenesis.
RL Biochem. Soc. Trans. 32:107-9 (2004).
RN [5]; RE0041701.
RX PUBMED: 11756538.
RA Qiu Y., Guo M., Huang S., Stein R.
RT Insulin gene transcription is mediated by interactions between the p300 coactivator and PDX-1, BETA2, and E47
RL Mol. Cell. Biol. 22:412-20 (2002).
RN [6]; RE0042333.
RX PUBMED: 15180990.
RA Martin C. C., Oeser J. K., O'Brien R. M.
RT Differential regulation of islet-specific glucose-6-phosphatase catalytic subunit-related protein gene transcription by Pax-6 and Pdx-1
RL J. Biol. Chem. 279:34277-89 (2004).
RN [7]; RE0045928.
RX PUBMED: 14729487.
RA Wang J., Elghazi L., Parker S. E., Kizilocak H., Asano M., Sussel L., Sosa-Pineda B.
RT The concerted activities of Pax4 and Nkx2.2 are essential to initiate pancreatic beta-cell differentiation
RL Dev. Biol. 266:178-89 (2004).
RN [8]; RE0047888.
RX PUBMED: 15496408.
RA Mosley A. L., Ozcan S.
RT The pancreatic duodenal homeobox-1 protein (Pdx-1) interacts with histone deacetylases Hdac-1 and Hdac-2 on low levels of glucose.
RL J. Biol. Chem. 279:54241-54247 (2004).
RN [9]; RE0055193.
RX PUBMED: 16166097.
RA Lebrun P., Montminy M. R., Van Obberghen E.
RT Regulation of the pancreatic duodenal homeobox-1 protein by DNA-dependent protein kinase.
RL J. Biol. Chem. 280:38203-38210 (2005).
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