AC T30879
XX
ID T30879
XX
DT 08.04.2012 (created); mkl.
DT 31.10.2014 (updated); yre.
CO Copyright (C), QIAGEN.
XX
FA BRD4-isoform1
XX
SY BRD4; Bromodomain-containing protein 4; HUNK1; Protein HUNK1.
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
XX
GE G007293 BRD4; HGNC: BRD4.
XX
SZ 1362 AA; 152.2 kDa (cDNA) (calc.).
XX
SQ MSAESGPGTRLRNLPVMGDGLETSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQT
SQ NQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYW
SQ NAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRG
SQ RGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMT
SQ VVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTI
SQ DPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGI
SQ LKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGA
SQ DVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVV
SQ APPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKE
SQ KDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYE
SQ SEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLK
SQ PSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETE
SQ MAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPP
SQ PPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLP
SQ QPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLL
SQ PQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPP
SQ PPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPP
SQ HPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLT
SQ HQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESI
SQ KAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMG
SQ SWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERM
SQ RSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSM
SQ LDQQRELARKREQERRRREAMAATIDMNFQSDLLSIFEENLF
XX
SC Swiss-Prot#O60885
XX
IN T30879 BRD4-isoform1; human, Homo sapiens.
IN T09446 c-Jun; Mammalia.
IN T10814 c-Myc:Max; Mammalia.
IN T08664 C/EBPalpha; Mammalia.
IN T09410 C/EBPbeta; Mammalia.
IN T08321 p53-isoform1; human, Homo sapiens.
IN T00671 p53; human, Homo sapiens.
IN T09500 p53; Mammalia.
IN T09133 YY1; Mammalia.
XX
DR TRANSPATH: MO000204850.
DR UniProtKB: O60885; BRD4_HUMAN.
XX
RN [1]; RE0083705.
RX PUBMED: 23317504.
RA Wu S. Y., Lee A. Y., Lai H. T., Zhang H., Chiang C. M.
RT Phospho switch triggers Brd4 chromatin binding and activator recruitment for gene-specific targeting.
RL Mol. Cell 49:843-857 (2013).
XX
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